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QuickView for STT3B (gene)


Gene Symbol:
STT3B Homo sapiens Homo sapiens
Full name:
STT3B, catalytic subunit of the oligosaccharyltransferase complex
Synonyms:
CDG1X, SIMP, STT3-B, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B, STT3, subunit of the oligosaccharyltransferase complex, homolog B, STT3B, subunit of the oligosaccharyltransferase complex (catalytic), dolichyl-diphosphooligosaccharide protein glycotransferase, homolog of yeast STT3, oligosaccharyl transferase subunit STT3B, source of immunodominant MHC-associated peptides homolog
Genomic Location:
Chr 3: 31549495-31652560
Description:
The protein encoded by this gene is a catalytic subunit of a protein complex that transfers oligosaccharides onto asparagine residues. Defects in this gene are a cause of congenital disorder of glycosylation Ix (CDG1X).
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3p23





GO Molecular Function

cation binding | dolichyl-diphosphooligosaccharide-protein glycotransferase activity | catalytic activity | transferase activity, transferring glycosyl groups | ion binding | protein binding | transferase activity, transferring hexosyl groups | transferase activity | oligosaccharyl transferase activity | metal ion binding

GO Biological Process

response to endoplasmic reticulum stress | proteolysis | peptidyl-amino acid modification | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | carbohydrate derivative catabolic process | glycoprotein biosynthetic process | catabolic process | response to topologically incorrect protein | protein N-linked glycosylation via asparagine | response to stimulus | co-translational protein modification | response to stress | cellular protein catabolic process | proteasomal protein catabolic process | carbohydrate derivative biosynthetic process | protein modification process | macromolecule glycosylation | cellular biosynthetic process | macromolecule modification | response to nitrogen compound | nitrogen compound metabolic process | cellular response to stress | protein catabolic process | biosynthetic process | proteasome-mediated ubiquitin-dependent protein catabolic process | ERAD pathway | protein metabolic process | response to organic substance | cellular macromolecule catabolic process | metabolic process | organic substance metabolic process | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | cellular protein metabolic process | protein N-linked glycosylation | response to unfolded protein | cellular macromolecule biosynthetic process | cellular protein modification process | carbohydrate derivative metabolic process | response to organonitrogen compound | protein glycosylation | ubiquitin-dependent ERAD pathway | glycosylation | cellular metabolic process | modification-dependent protein catabolic process | glycoprotein catabolic process | glycoprotein metabolic process | post-translational protein modification | macromolecule metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | catalytic complex | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | transferase complex | membrane-bounded organelle | organelle | intracellular | membrane | oligosaccharyltransferase complex