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QuickView for SUCNR1 (gene)


Gene Symbol:
SUCNR1 Homo sapiens Homo sapiens
Full name:
succinate receptor 1
Synonyms:
GPR91, succinate receptor 1, G-protein coupled receptor 91, P2Y purinoceptor 1
Genomic Location:
Chr 3: 153074127-153082340
Description:
This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Bos taurus Pan troglodytes Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3q25.1


Transcripts Names
NM_033050
Protein Names
A8K305
Q9BXA5
Q8TDQ8



GO Molecular Function

transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity

GO Biological Process

positive regulation of locomotion | regulation of systemic arterial blood pressure by hormone | establishment of localization | response to metal ion | glucose homeostasis | cellular process | secretion | localization | protein transport | macromolecule localization | regulation of chemotaxis | regulation of angiotensin metabolic process | response to inorganic substance | regulation of cellular process | leukocyte activation | regulation of metabolic process | regulation of systemic arterial blood pressure mediated by a chemical signal | renin secretion into blood stream | G-protein coupled receptor activity | response to stimulus | interleukin-1 beta production | leukocyte activation involved in immune response | secretion by cell | blood circulation | G-protein coupled receptor signaling pathway | positive regulation of inflammatory response | positive regulation of chemotaxis | organic substance transport | regulation of blood pressure | regulation of systemic arterial blood pressure by renin-angiotensin | regulation of systemic arterial blood pressure | regulation of nitrogen compound metabolic process | peptide transport | macrophage activation involved in immune response | peptide secretion | endocrine process | cell communication | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | homeostatic process | regulation of locomotion | cytokine production | amide transport | chemical homeostasis | macrophage activation | immune response | renal system process | regulation of systemic arterial blood pressure by circulatory renin-angiotensin | establishment of protein localization | cell activation | signaling | protein localization | renal system process involved in regulation of systemic arterial blood pressure | response to calcium ion | immune system process | protein secretion | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure | regulation of inflammatory response | carbohydrate homeostasis | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | membrane