QuickView for SYNCRIP;jsessionid=F4C76F25907D3E6539736709FFBA13C5 (gene)

Gene Symbol:

SYNCRIP Homo sapiens

Full name:

synaptotagmin binding cytoplasmic RNA interacting protein

Synonyms:

GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, heterogeneous nuclear ribonucleoprotein Q, NS1-associated protein 1, glycine- and tyrosine-rich RNA-binding protein

Genomic Location:

Chr 6: 86380658-86409746

Description:

This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA ma...

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This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CTTGTAT_MIR381 ,  SP1_01 ,  TFIIA_Q6 ,  PR_02 ,  CEBPA_01 ,  GATA1_01 ,  CREBP1CJUN_01 ,  ATF6_01 ,  ARNT_01 ,  HOXA4_Q2 ,  GATA3_01 ,  PR_01 ,  TTGCWCAAY_CEBPB_02 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  SRF_Q6 ,  E2F4DP1_01 ,  NGFIC_01 ,  GAGACTG_MIR452 ,  MAX_01 ,  CEBP_Q2_01 ,  IPF1_Q4 ,  HP1SITEFACTOR_Q6 ,  VDR_Q6 ,  ARNT_02 ,  TAAYNRNNTCC_UNKNOWN ,  ZIC3_01 ,  GR_Q6_01 ,  MAF_Q6 ,  EGR2_01 ,  GGGAGGRR_MAZ_Q6 ,  AR_Q6 ,  MYCMAX_02 ,  CEBPB_01 ,  LEF1_Q6 ,  DBP_Q6 ,  E2F1_Q6_01 ,  CAGGTG_E12_Q6 ,  CAGNYGKNAAA_UNKNOWN ,  TTCYRGAA_UNKNOWN ,  YY1_01 ,  GR_Q6 ,  EVI1_02 ,  RRAGTTGT_UNKNOWN ,  AR_03 ,  MYCMAX_01 ,  GGGCGGR_SP1_Q6 ,  GGCNKCCATNK_UNKNOWN ,  TGCTGAY_UNKNOWN ,  E2F1DP2_01 ,  CEBPB_02 ,  E2F1_Q3_01 ,  MGGAAGTG_GABP_B ,  TGCCAAR_NF1_Q6 ,  SPZ1_01 ,  KCCGNSWTTT_UNKNOWN ,  GATA2_01 ,  E2F1DP1_01 ,  AR_Q2 ,  RNGTGGGC_UNKNOWN ,  CEBP_Q3 ,  YGCGYRCGC_UNKNOWN ,  GR_01 ,  CHOP_01 ,  WTTGKCTG_UNKNOWN ,  E2F_02 ,  ZIC2_01 ,  KMCATNNWGGA_UNKNOWN ,  TCCATTKW_UNKNOWN ,  CCGNMNNTNACG_UNKNOWN ,  ICSBP_Q6 ,  E2F4DP2_01 ,  WCAANNNYCAG_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  TAANNYSGCG_UNKNOWN ,  KTGGYRSGAA_UNKNOWN ,  ZF5_B ,  FOXM1_01 ,  P300_01 ,  GCTNWTTGK_UNKNOWN ,  TGACATY_UNKNOWN ,  ACCATTT_MIR522 ,  CREB_Q2_01 ,  PAX4_01 ,  SRF_C ,  GGGTGGRR_PAX4_03 ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01 ,  STAT5A_02

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-382 ,  Predicted Gene Targets for miR-375

Cytogenetic Map:

6q14.3

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