QuickView for SYT5 (gene)

Gene Symbol:

SYT5 Homo sapiens

Full name:

synaptotagmin 5

Synonyms:

synaptotagmin-5, synaptotagmin V, sytV

Genomic Location:

Chr 19: 60376281-60383532

Description:

Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium recept...

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Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

POU6F1_01 ,  GABP_B ,  CAGGTA_AREB6_01 ,  RFX1_02 ,  GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  GACAATC_MIR219 ,  GTTGNYNNRGNAAC_UNKNOWN ,  CETS1P54_01 ,  SCGGAAGY_ELK1_02 ,  NRF2_01 ,  TGCTTTG_MIR330 ,  ELK1_02

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-219 ,  Predicted Gene Targets for miR-330

Cytogenetic Map:

19q13.42::11p

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