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QuickView for Scn10a (gene)


Gene Symbol:
SCN10A Homo sapiens Homo sapiens
Full name:
sodium voltage-gated channel alpha subunit 10
Synonyms:
FEPS2, Nav1.8, PN3, SNS, hPN3, sodium channel protein type 10 subunit alpha, peripheral nerve sodium channel 3, sodium channel protein type X subunit alpha, sodium channel, voltage-gated, type X, alpha polypeptide, sodium channel, voltage-gated, type X, alpha subunit, voltage-gated sodium channel subunit alpha Nav1.8
Genomic Location:
Chr 3: 38713841-38810505
Description:
The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy. Alternative splicing r...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr 3
3p22.2





GO Molecular Function

voltage-gated ion channel activity | passive transmembrane transporter activity | voltage-gated sodium channel activity | transmembrane transporter activity | ion gated channel activity | ion channel binding | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | protein binding | metal ion transmembrane transporter activity | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of muscle system process | regulation of localization | establishment of localization | membrane depolarization during action potential | voltage-gated ion channel activity | AV node cell to bundle of His cell signaling | cellular process | localization | odontogenesis | passive transmembrane transporter activity | metal ion transport | regulation of cellular process | voltage-gated sodium channel activity | transmembrane transporter activity | bundle of His cell action potential | ion gated channel activity | regulation of blood circulation | regulation of heart rate | neuronal action potential | cell-cell signaling | regulation of membrane potential | system development | multicellular organism development | regulation of muscle contraction | ion transmembrane transport | nervous system process | sodium ion transport | cation transmembrane transporter activity | regulation of membrane depolarization | monovalent inorganic cation transport | animal organ morphogenesis | ion transmembrane transporter activity | bundle of His cell to Purkinje myocyte communication | sensory perception of pain | cell-cell signaling involved in cardiac conduction | regulation of heart contraction | regulation of striated muscle contraction | cell communication | regulation of atrial cardiac muscle cell membrane depolarization | odontogenesis of dentin-containing tooth | regulation of cardiac muscle contraction | homeostatic process | cation transmembrane transport | metal ion transmembrane transporter activity | anatomical structure development | AV node cell action potential | AV node cell to bundle of His cell communication | cell communication involved in cardiac conduction | chemical homeostasis | membrane depolarization | sodium ion transmembrane transport | animal organ development | ion homeostasis | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | regulation of ion transmembrane transport | sodium channel activity | cation channel activity | sensory perception | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | anatomical structure morphogenesis | cation transport | channel activity | regulation of ion transport | developmental process | regulation of transport | cardiac muscle cell action potential | transmission of nerve impulse | ion channel activity | ion transport | substrate-specific channel activity | cardiac conduction | multicellular organismal process

GO Cellular Component

integral component of membrane | voltage-gated sodium channel complex | neuron projection | cell | plasma membrane protein complex | intrinsic component of membrane | clathrin complex | cytoplasm | protein-containing complex | cell projection | plasma membrane | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | clathrin coat | organelle | sodium channel complex | extracellular space | cell periphery | axon | transmembrane transporter complex | cation channel complex | ion channel complex | intracellular | membrane | intrinsic component of plasma membrane | membrane coat