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QuickView for Sema3D (gene)


Gene Symbol:
SEMA3D Homo sapiens Homo sapiens
Full name:
semaphorin 3D
Synonyms:
Sema-Z2, coll-2, semaphorin-3D, collapsin 2, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
Genomic Location:
Chr 7: 84462805-84589183
Description:
This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin like domain and a C-terminal basic domain. The protein encoded by this gene binds neuropilin and plays an important role in c...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 7
7q21.11





GO Molecular Function

chemorepellent activity | signaling receptor binding | semaphorin receptor binding | molecular function regulator | neuropilin binding | protein binding | receptor regulator activity | receptor ligand activity

GO Biological Process

positive regulation of locomotion | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cell development | regulation of localization | regulation of axon extension involved in axon guidance | negative regulation of cellular process | cell differentiation | nervous system development | neurogenesis | positive regulation of cellular component movement | generation of neurons | mesenchyme development | cellular process | negative regulation of axonogenesis | regulation of cell motility | localization | negative regulation of developmental growth | chemorepellent activity | regulation of chemotaxis | regulation of neuron projection development | tissue development | regulation of cell differentiation | regulation of cellular process | negative regulation of chemotaxis | regulation of axon guidance | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | response to stimulus | mesenchymal cell development | negative regulation of neuron projection development | regulation of cellular component size | regulation of axon extension | molecular function regulator | locomotion | system development | regulation of signal transduction | negative regulation of growth | multicellular organism development | cell migration | regulation of axonogenesis | regulation of neuron differentiation | regulation of cell migration | regulation of cellular component movement | stem cell differentiation | positive regulation of cell migration | neural crest cell migration | cell communication | regulation of locomotion | negative regulation of cell growth | regulation of signaling receptor activity | receptor regulator activity | regulation of cell morphogenesis involved in differentiation | regulation of growth | negative regulation of cell projection organization | negative regulation of axon extension involved in axon guidance | anatomical structure development | cell surface receptor signaling pathway | mesenchymal cell differentiation | negative regulation of axon extension | receptor ligand activity | animal organ development | negative regulation of neuron differentiation | negative regulation of cellular component movement | stem cell development | regulation of cell communication | signaling | cell development | regulation of developmental growth | regulation of cell size | regulation of nervous system development | regulation of developmental process | developmental process | regulation of cell growth | negative chemotaxis | neural crest cell differentiation | regulation of cell projection organization | ameboidal-type cell migration | positive regulation of cell motility | negative regulation of cell development | chemotaxis | semaphorin-plexin signaling pathway | negative regulation of locomotion | neural crest cell development | negative regulation of cell differentiation | regulation of cellular component organization | signal transduction | regulation of signaling | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | extracellular region | extracellular space | cell periphery | membrane | intrinsic component of plasma membrane