QuickView for SerpinG1 (gene)

Gene Symbol:

SERPING1 Homo sapiens

Full name:

serpin family G member 1

Synonyms:

C1IN, C1INH, C1NH, HAE1, HAE2, plasma protease C1 inhibitor, C1 esterase inhibitor, C1-inhibiting factor, complement component 1 inhibitor, serine/cysteine proteinase inhibitor clade G member 1, serpin G1, serpin peptidase inhibitor clade G member 1, serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

Genomic Location:

Chr 11: 57121603-57138902

Description:

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in mult...

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This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CDPCR3HD_01 ,  TAL1BETAE47_01 ,  STAT5B_01 ,  CDPCR1_01 ,  STAT3_01 ,  STAT_01 ,  WTTGKCTG_UNKNOWN ,  RGTTAMWNATT_HNF1_01 ,  PAX_Q6 ,  TTCYNRGAA_STAT5B_01 ,  STAT1_01 ,  STAT5A_01 ,  AACTTT_UNKNOWN

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Cytogenetic Map:

11q12.1

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