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QuickView for TAC1R (gene)


Gene Symbol:
TACR1 Homo sapiens Homo sapiens
Full name:
tachykinin receptor 1
Synonyms:
NK1R, NKIR, SPR, TAC1R, substance-P receptor, NK-1 receptor, NK-1R, tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
Genomic Location:
Chr 2: 75129738-75279781
Description:
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosph...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 2
2p12


Transcripts Names
NM_001058
NM_015727
Protein Names
A8K150
P25103



GO Molecular Function

tachykinin receptor activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | neuropeptide receptor activity | substance P receptor activity | signaling receptor activity | protein binding | peptide receptor activity | G-protein coupled peptide receptor activity

GO Biological Process

behavioral response to pain | regulation of supramolecular fiber organization | positive regulation of action potential | regulation of blood vessel diameter | regulation of muscle system process | tachykinin receptor activity | positive regulation of locomotion | positive regulation of blood circulation | detection of stimulus | regulation of systemic arterial blood pressure by hormone | long-term memory | positive regulation of cellular component organization | regulation of localization | response to isoquinoline alkaloid | insemination | regulation of immune system process | response to hormone | positive regulation of lymphocyte activation | positive regulation of epithelial cell proliferation | defense response | regulation of smooth muscle contraction | response to drug | cellular chemical homeostasis | regulation of organelle organization | positive regulation of cellular component movement | regulation of renal sodium excretion | response to antibiotic | cellular process | neuropeptide signaling pathway | response to morphine | regulation of cell motility | cellular homeostasis | positive regulation of synaptic transmission | response to progesterone | response to estradiol | regulation of digestive system process | multicellular organismal reproductive process | learning | response to inorganic substance | drinking behavior | positive regulation of vasoconstriction | positive regulation of uterine smooth muscle contraction | regulation of cellular process | regulation of cytosolic calcium ion concentration | neurological system process involved in regulation of systemic arterial blood pressure | positive regulation of renal sodium excretion | smooth muscle contraction | regulation of systemic arterial blood pressure mediated by a chemical signal | calcium ion homeostasis | positive regulation of epithelial cell migration | G-protein coupled receptor activity | muscle contraction | associative learning | response to stimulus | positive regulation of blood pressure | response to pain | positive regulation of immune system process | positive regulation of flagellated sperm motility | regulation of excretion | positive regulation of saliva secretion | regulation of blood vessel size | response to stress | positive regulation of lymphocyte proliferation | response to ozone | regulation of cell proliferation | positive regulation of actin filament bundle assembly | regulation of blood circulation | regulation of smooth muscle cell migration | positive regulation of cell activation | reproduction | response to alcohol | response to temperature stimulus | neuropeptide receptor activity | positive regulation of hormone secretion | blood circulation | G-protein coupled receptor signaling pathway | modulation of chemical synaptic transmission | metal ion homeostasis | urinary bladder smooth muscle contraction | response to ethanol | positive regulation of stress fiber assembly | regulation of membrane potential | detection of abiotic stimulus | response to nitrogen compound | positive regulation of mononuclear cell proliferation | response to nicotine | reproductive process | positive regulation of organelle organization | regulation of synaptic transmission, cholinergic | regulation of actin cytoskeleton organization | regulation of synaptic transmission, GABAergic | regulation of actin filament organization | learning or memory | tachykinin receptor signaling pathway | regulation of muscle contraction | regulation of actomyosin structure organization | regulation of hormone levels | regulation of hormone secretion | regulation of ossification | regulation of flagellated sperm motility | positive regulation of secretion | response to ketone | response to lipid | nervous system process | copulation | regulation of blood pressure | excretion | regulation of systemic arterial blood pressure by renin-angiotensin | regulation of systemic arterial blood pressure | regulation of lymphocyte activation | cellular ion homeostasis | substance P receptor activity | response to ammonium ion | aggressive behavior | positive regulation of cytosolic calcium ion concentration | regulation of cell migration | regulation of vascular permeability | regulation of cellular component movement | response to oxidative stress | positive regulation of digestive system process | cognition | positive regulation of cell migration | regulation of uterine smooth muscle contraction | sensory perception of pain | eating behavior | positive regulation of ossification | regulation of blood volume by renin-angiotensin | response to toxic substance | response to xenobiotic stimulus | cation homeostasis | regulation of leukocyte migration | cellular cation homeostasis | endocrine process | cell communication | positive regulation of smooth muscle contraction | inflammatory response | positive regulation of cytoskeleton organization | smooth muscle contraction involved in micturition | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of locomotion | positive regulation of synaptic transmission, GABAergic | regulation of tube size | positive regulation of transport | sperm ejaculation | multicellular organism reproduction | multicellular organismal response to stress | angiotensin-mediated drinking behavior | response to organic substance | response to mechanical stimulus | regulation of saliva secretion | positive regulation of vascular permeability | regulation of vasoconstriction | positive regulation of supramolecular fiber organization | positive regulation of leukocyte activation | regulation of body fluid levels | regulation of tube diameter | chemical homeostasis | brain renin-angiotensin system | regulation of secretion | behavior | positive regulation of muscle contraction | positive regulation of cellular component biogenesis | mating | response to reactive oxygen species | regulation of cell activation | positive regulation of leukocyte migration | micturition | response to heat | ion homeostasis | response to alkaloid | phospholipase C-activating G-protein coupled receptor signaling pathway | renal system process | positive regulation of synaptic transmission, cholinergic | regulation of stress fiber assembly | memory | sensory perception | regulation of epithelial cell migration | regulation of action potential | regulation of cell communication | signaling | feeding behavior | G-protein coupled peptide receptor activity | response to organic cyclic compound | regulation of epithelial cell proliferation | operant conditioning | regulation of actin filament bundle assembly | regulation of transport | response to organonitrogen compound | cellular metal ion homeostasis | response to electrical stimulus | response to anesthetic | regulation of actin filament-based process | acute inflammatory response | regulation of smooth muscle cell proliferation | positive regulation of cell motility | response to steroid hormone | divalent inorganic cation homeostasis | sexual reproduction | regulation of cellular component organization | regulation of cytoskeleton organization | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | response to auditory stimulus | multicellular organismal process

GO Cellular Component

sperm flagellum | integral component of membrane | dendrite | sperm midpiece | neuron projection | somatodendritic compartment | cell body | cell | intrinsic component of membrane | cytoplasm | 9+2 motile cilium | motile cilium | dendritic tree | cell projection | plasma membrane | cilium | integral component of plasma membrane | organelle | cell periphery | cell surface | intracellular | membrane | intrinsic component of plasma membrane | sperm head