QuickView for TAFA-4 (gene)

Gene Symbol:

FAM19A4 Homo sapiens

Full name:

family with sequence similarity 19 member A4, C-C motif chemokine like

Synonyms:

TAFA-4, TAFA4, protein FAM19A4, chemokine-like protein TAFA-4, family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

Genomic Location:

Chr 3: 68863607-69064401

Description:

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the ...

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This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  TGANTCA_AP1_C ,  CACGTG_MYC_Q2 ,  NFY_Q6_01 ,  CAGGTG_E12_Q6 ,  MYCMAX_01 ,  ACCAAAG_MIR9 ,  NFY_01 ,  RNGTGGGC_UNKNOWN ,  NMYC_01 ,  TGACAGNY_MEIS1_01 ,  GCTNWTTGK_UNKNOWN ,  AACTTT_UNKNOWN ,  LMO2COM_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-9

Cytogenetic Map:

3p14.1

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