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QuickView for TAFF1 (gene)


Gene Symbol:
ZFYVE1 Homo sapiens Homo sapiens
Full name:
zinc finger FYVE-type containing 1
Synonyms:
DFCP1, PPP1R172, SR3, TAFF1, ZNFN2A1, zinc finger FYVE domain-containing protein 1, double FYVE-containing protein 1, phosphoinositide-binding protein SR3, protein phosphatase 1, regulatory subunit 172, tandem FYVE fingers-1 protein, zinc finger protein, subfamily 2A, member 1, zinc finger, FYVE domain containing 1
Genomic Location:
Chr 14: 72505912-72563592
Description:
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 14
14q24.2





GO Molecular Function

cation binding | lipid binding | phospholipid binding | phosphatidylinositol-3,4-bisphosphate binding | anion binding | phosphatidylinositol bisphosphate binding | ion binding | phosphatidylinositol-3,4,5-trisphosphate binding | protein binding | zinc ion binding | phosphatidylinositol binding | transition metal ion binding | 1-phosphatidylinositol binding | metal ion binding | phosphatidylinositol phosphate binding

GO Biological Process

response to extracellular stimulus | regulation of dephosphorylation | response to nutrient levels | macroautophagy | negative regulation of cellular process | regulation of phosphatase activity | cellular response to extracellular stimulus | cellular process | cellular response to starvation | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | negative regulation of phosphatase activity | response to stimulus | response to stress | response to starvation | negative regulation of metabolic process | cellular response to nutrient levels | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of catalytic activity | cellular response to stress | autophagy | cell communication | regulation of cellular metabolic process | metabolic process | regulation of phosphate metabolic process | negative regulation of molecular function | negative regulation of dephosphorylation | negative regulation of hydrolase activity | cellular metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

ER-mitochondrion membrane contact site | Golgi stack | intracellular membrane-bounded organelle | extrinsic component of organelle membrane | extrinsic component of membrane | organelle membrane | extrinsic component of omegasome membrane | cell | organelle membrane contact site | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | phagophore assembly site | endomembrane system | vacuole | perinuclear region of cytoplasm | membrane-bounded organelle | organelle | omegasome | intracellular | autophagosome | membrane