QuickView for TAFI95 (gene)

Gene Symbol:

TAF1C Homo sapiens

Full name:

TATA-box binding protein associated factor, RNA polymerase I subunit C

Synonyms:

MGC:39976, SL1, TAFI110, TAFI95, TATA box-binding protein-associated factor RNA polymerase I subunit C, RNA polymerase I-specific TBP-associated factor 110 kDa, SL1, 110kD subunit, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa, TATA box-binding protein-associated factor 1C, TATA-box binding protein associated factor, RNA polymerase I, C, TBP-associated factor 1C, transcription factor SL1, transcription initiation factor SL1/TIF-IB subunit C

Genomic Location:

Chr 16: 82768962-82778163

Description:

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory s...

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Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris ,  Gallus gallus

External Links:

Entrez Gene

Cytogenetic Map:

16q24.1

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