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QuickView for TAFII130 (gene)


Gene Symbol:
TAF4 Homo sapiens Homo sapiens
Full name:
TATA-box binding protein associated factor 4
Synonyms:
TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135, transcription initiation factor TFIID subunit 4, RNA polymerase II TBP-associated factor subunit C, TAF(II)130, TAF(II)135, TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa, TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135 kD, TAFII-130, TAFII-135, TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD, TBP-associated factor 4, transcription initiation factor TFIID 130 kDa subunit, transcription initiation factor TFIID 135 kD subunit, transcription initiation factor TFIID 135 kDa subunit
Genomic Location:
Chr 20: 59983249-60074261
Description:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as...
Orthologs:
Mus musculus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 20
20q13.33


Transcripts Names
NM_003185



GO Molecular Function

RNA polymerase II transcription factor activity, sequence-specific DNA binding | aryl hydrocarbon receptor binding | nucleic acid binding | signaling receptor binding | DNA binding | protein heterodimerization activity | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | organic cyclic compound binding | transcription coactivator activity | protein binding | DNA-binding transcription factor activity | transcription factor binding | protein dimerization activity | transcription coregulator activity | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | developmental process involved in reproduction | ovarian follicle development | gonad development | female gonad development | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of cellular biosynthetic process | cellular process | reproductive system development | positive regulation of nitrogen compound metabolic process | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | development of primary sexual characteristics | cellular nitrogen compound biosynthetic process | development of primary female sexual characteristics | protein-DNA complex assembly | reproduction | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | regulation of gene expression | regulation of signal transduction by p53 class mediator | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | DNA-templated transcriptional preinitiation complex assembly | RNA polymerase II transcriptional preinitiation complex assembly | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | viral process | protein-containing complex assembly | DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | regulation of cell communication | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | reproductive structure development | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | sex differentiation | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

nuclear transcription factor complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | SAGA-type complex | cell | nuclear lumen | transcription factor complex | MLL1/2 complex | histone acetyltransferase complex | cytoplasm | intracellular organelle | MLL1 complex | histone methyltransferase complex | protein-containing complex | methyltransferase complex | nucleoplasm | transcription factor TFTC complex | chromatin | nuclear chromosome | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | protein acetyltransferase complex | nuclear chromatin | cytosol | intracellular | RNA polymerase II, holoenzyme