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QuickView for TAFII150 (gene)


Gene Symbol:
TAF2 Homo sapiens Homo sapiens
Full name:
TATA-box binding protein associated factor 2
Synonyms:
CIF150, MRT40, TAF2B, TAFII150, transcription initiation factor TFIID subunit 2, 150 kDa cofactor of initiator function, RNA polymerase II TBP-associated factor subunit B, TAF(II)150, TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa, TATA box binding protein (TBP)-associated factor, RNA polymerase II, B, 150kD, TBP-associated factor 150 kDa, cofactor of initiator function, 150kD subunit, transcription initiation factor TFIID 150 kDa subunit
Genomic Location:
Chr 8: 120812195-120914255
Description:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8
8q24.12





GO Molecular Function

sequence-specific DNA binding | transcription factor activity, transcription factor binding | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcription factor activity, RNA polymerase II transcription factor binding | nucleic acid binding | chromatin binding | DNA binding | RNA polymerase II transcription factor activity, TBP-class protein binding | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | transcription factor activity, RNA polymerase II transcription factor binding | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | cellular nitrogen compound biosynthetic process | protein-DNA complex assembly | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of signal transduction | regulation of gene expression | cell cycle | regulation of signal transduction by p53 class mediator | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | RNA polymerase II transcription factor activity, TBP-class protein binding | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | G2/M transition of mitotic cell cycle | cellular protein-containing complex assembly | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | DNA-templated transcriptional preinitiation complex assembly | mitotic cell cycle phase transition | RNA polymerase II transcriptional preinitiation complex assembly | regulation of cellular metabolic process | cell cycle G2/M phase transition | regulation of RNA metabolic process | protein-containing complex assembly | DNA-binding transcription factor activity | response to organic substance | regulation of intracellular signal transduction | mitotic cell cycle | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | regulation of cell communication | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | cell cycle phase transition | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | positive regulation of metabolic process | cellular metabolic process | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | SAGA-type complex | cell | nuclear lumen | transcription factor complex | histone acetyltransferase complex | intracellular organelle | protein-containing complex | nucleoplasm | transcription factor TFTC complex | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | protein acetyltransferase complex | intracellular | RNA polymerase II, holoenzyme