QuickView for TAFII170 (gene)
- Gene Symbol:
- BTAF1
Homo sapiens - Full name:
- B-TFIID TATA-box binding protein associated factor 1
- Synonyms:
- MOT1, TAF(II)170, TAF172, TAFII170, TATA-binding protein-associated factor 172, ATP-dependent helicase BTAF1, B-TFIID transcription factor-associated 170 kDa subunit, BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae), Mot1 homolog, TBP-associated factor 172
- Genomic Location:
- Chr 10: 93673716-93780062
- Description:
-
This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate wi...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-1 , Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-135 , Predicted Gene Targets for miR-148 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-214 , Predicted Gene Targets for miR-23 , Predicted Gene Targets for miR-24 , Predicted Gene Targets for miR-323 , Predicted Gene Targets for miR-381
- Cytogenetic Map:
-
10q23.32
GO Molecular Function
nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | DNA binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | DNA-binding transcription factor activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | helicase activity | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
negative regulation of cellular process | negative regulation of RNA biosynthetic process | negative regulation of nucleic acid-templated transcription | negative regulation of cellular metabolic process | regulation of binding | regulation of cellular process | regulation of metabolic process | negative regulation of metabolic process | regulation of chromatin binding | regulation of nucleic acid-templated transcription | regulation of gene expression | negative regulation of chromatin binding | regulation of nitrogen compound metabolic process | negative regulation of binding | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of molecular function | regulation of transcription, DNA-templated
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
