QuickView for TAFII31L (gene)

Gene Symbol:

TAF9B Homo sapiens

Full name:

TATA-box binding protein associated factor 9b

Synonyms:

DN-7, DN7, TAF9L, TAFII31L, TFIID-31, transcription initiation factor TFIID subunit 9B, TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa, TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa, TBP-associated factor 9L, neuronal cell death-related protein 7, transcription initiation factor IID, 31kD subunit, transcription-associated factor TAFII31L

Genomic Location:

Chr X: 77271901-77281835

Description:

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as...

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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTCAGGG_MIR125B_MIR125A ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  AAACCAC_MIR140 ,  ACACTGG_MIR199A_MIR199B

Cytogenetic Map:

Xq21.1

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