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QuickView for TAFII80 (gene)


Gene Symbol:
TAF6 Homo sapiens Homo sapiens
Full name:
TATA-box binding protein associated factor 6
Synonyms:
ALYUS, MGC:8964, TAF(II)70, TAF(II)80, TAF2E, TAFII-70, TAFII-80, TAFII70, TAFII80, TAFII85, transcription initiation factor TFIID subunit 6, RNA polymerase II TBP-associated factor subunit E, TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa, TATA box binding protein (TBP)-associated factor, RNA polymerase II, E, 70/85kD, transcription initiation factor TFIID 70 kDa subunit
Genomic Location:
Chr 7: 99542629-99554915
Description:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 7
7q22.1





GO Molecular Function

aryl hydrocarbon receptor binding | RNA polymerase II activating transcription factor binding | nucleic acid binding | signaling receptor binding | DNA binding | protein heterodimerization activity | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | activating transcription factor binding | protein dimerization activity | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | snRNA metabolic process | negative regulation of cellular process | cellular process | chromatin organization | regulation of cell cycle | snRNA transcription | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | cellular nitrogen compound biosynthetic process | snRNA transcription by RNA polymerase II | protein-DNA complex assembly | cellular nitrogen compound metabolic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of signal transduction | ncRNA transcription | regulation of gene expression | regulation of signal transduction by p53 class mediator | regulation of nitrogen compound metabolic process | biosynthetic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | DNA-templated transcriptional preinitiation complex assembly | RNA polymerase II transcriptional preinitiation complex assembly | regulation of cellular metabolic process | regulation of RNA metabolic process | protein-containing complex assembly | DNA-binding transcription factor activity | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | negative regulation of cell cycle | regulation of cell communication | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | organelle organization | ncRNA metabolic process | heterocycle metabolic process | chromosome organization | cellular metabolic process | regulation of signaling | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | SAGA complex | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | SAGA-type complex | cell | nuclear lumen | transcription factor complex | MLL1/2 complex | histone acetyltransferase complex | cytoplasm | intracellular organelle | MLL1 complex | histone methyltransferase complex | protein-containing complex | methyltransferase complex | nucleoplasm | transcription factor TFTC complex | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | protein acetyltransferase complex | cytosol | intracellular | SLIK (SAGA-like) complex | RNA polymerase II, holoenzyme