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QuickView for TAFIII90 (gene)


Gene Symbol:
BRF1 Homo sapiens Homo sapiens
Full name:
BRF1, RNA polymerase III transcription initiation factor subunit
Synonyms:
BRF, BRF-1, CFDS, GTF3B, HEL-S-76p, TAF3B2, TAF3C, TAFIII90, TF3B90, TFIIIB90, hBRF, transcription factor IIIB 90 kDa subunit, B - related factor 1, BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB, BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit, TATA box binding protein (TBP)-associated factor 3C, TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2, TBP - associated factor, RNA polymerase III, 90kD, epididymis secretory sperm binding protein Li 76p, general transcription factor IIIB, 90kD subunit
Genomic Location:
Chr 14: 104746668-104838374
Description:
This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding differe...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 14
14q32.33





GO Molecular Function

cation binding | ion binding | protein binding | transcription factor binding | TBP-class protein binding | metal ion binding

GO Biological Process

RNA metabolic process | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase III | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | cellular nitrogen compound biosynthetic process | positive regulation of transcription by RNA polymerase III | protein-DNA complex assembly | cellular nitrogen compound metabolic process | tRNA transcription | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | ncRNA transcription | regulation of gene expression | transcription initiation from RNA polymerase III promoter | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | rRNA transcription | biosynthetic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | rRNA metabolic process | DNA-templated transcriptional preinitiation complex assembly | regulation of cellular metabolic process | regulation of RNA metabolic process | tRNA metabolic process | protein-containing complex assembly | metabolic process | regulation of RNA biosynthetic process | transcription by RNA polymerase III | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | ncRNA metabolic process | positive regulation of nucleic acid-templated transcription | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | nucleoplasm | transcription factor TFIIIB complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular