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QuickView for TAG7 (gene)


Gene Symbol:
PGLYRP1 Homo sapiens Homo sapiens
Full name:
peptidoglycan recognition protein 1
Synonyms:
PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L, peptidoglycan recognition protein 1, TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein)
Genomic Location:
Chr 19: 51214281-51218163
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Pan troglodytes Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr 19
19q13.32


Transcripts Names
NM_005091
Protein Names
O75594
Q4VB36



GO Molecular Function

N-acetylmuramoyl-L-alanine amidase activity | cation binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | peptidoglycan receptor activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | signaling receptor activity | ion binding | signaling pattern recognition receptor activity | peptidoglycan binding | zinc ion binding | glycosaminoglycan binding | transition metal ion binding | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | metal ion binding

GO Biological Process

positive regulation of immune response | negative regulation of lymphocyte differentiation | negative regulation of leukocyte activation | positive regulation of cell killing | negative regulation of immune system process | exocytosis | detection of stimulus | immune response-regulating signaling pathway | neutrophil activation | defense response to other organism | establishment of localization | regulation of immune system process | negative regulation of cellular process | defense response | peptidoglycan catabolic process | innate immune response-activating signal transduction | cellular process | secretion | organic substance catabolic process | negative regulation of inflammatory response | leukocyte degranulation | localization | carbohydrate derivative catabolic process | positive regulation of killing of cells of other organism | glycosaminoglycan catabolic process | regulation of cytolysis | regulation of cell differentiation | interspecies interaction between organisms | regulation of immune response | regulation of cellular process | leukocyte activation | catabolic process | regulation of natural killer cell activation | response to stimulus | neutrophil degranulation | positive regulation of innate immune response | positive regulation of immune system process | response to stress | negative regulation of lymphocyte activation | leukocyte activation involved in immune response | negative regulation of interferon-gamma production | activation of innate immune response | secretion by cell | immune response-activating signal transduction | growth of symbiont in host | negative regulation of hemopoiesis | regulation of lymphocyte differentiation | peptidoglycan receptor activity | response to external biotic stimulus | nitrogen compound metabolic process | pattern recognition receptor signaling pathway | leukocyte mediated immunity | regulation of killing of cells of other organism | cell killing | modification of morphology or physiology of other organism | negative regulation of cytokine production | regulation of lymphocyte activation | vesicle-mediated transport | negative regulation of immune response | regulated exocytosis | positive regulation of cytolysis | peptidoglycan metabolic process | response to bacterium | cell communication | negative regulation of natural killer cell differentiation involved in immune response | positive regulation of cytolysis in other organism | antimicrobial humoral immune response mediated by antimicrobial peptide | signaling pattern recognition receptor activity | negative regulation of cell activation | humoral immune response | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | defense response to bacterium | negative regulation of natural killer cell activation | antimicrobial humoral response | regulation of natural killer cell differentiation involved in immune response | activation of immune response | regulation of innate immune response | regulation of hemopoiesis | killing of cells of other organism | metabolic process | immune response | organic substance metabolic process | regulation of cell activation | detection of bacterium | cell activation | organonitrogen compound catabolic process | regulation of natural killer cell differentiation | defense response to Gram-positive bacterium | signaling | regulation of cytokine production | response to biotic stimulus | regulation of developmental process | detection of biotic stimulus | carbohydrate derivative metabolic process | innate immune response | neutrophil mediated immunity | regulation of interferon-gamma production | immune system process | regulation of inflammatory response | negative regulation of cell differentiation | response to other organism | signal transduction | glycosaminoglycan metabolic process | macromolecule metabolic process

GO Cellular Component

secretory granule | tertiary granule | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | endocytic vesicle lumen | intracellular organelle | secretory vesicle | endomembrane system | vesicle | phagocytic vesicle lumen | extracellular exosome | specific granule | extracellular region | membrane-bounded organelle | extracellular vesicle | specific granule lumen | organelle | extracellular space | tertiary granule lumen | membrane-enclosed lumen | secretory granule lumen | intracellular vesicle | endocytic vesicle | intracellular | vesicle lumen | phagocytic vesicle