QuickView for TAGE4 (gene)
- Gene Symbol:
- PVR
Homo sapiens - Full name:
- poliovirus receptor
- Synonyms:
- CD155, HVED, NECL5, Necl-5, PVS, TAGE4, poliovirus receptor, nectin-like protein 5
- Genomic Location:
- Chr 19: 49839066-49858690
- Description:
-
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
19q13.31
GO Molecular Function
signaling receptor activity | identical protein binding | cell adhesion molecule binding | protein binding | protein homodimerization activity | protein dimerization activity | virus receptor activity
GO Biological Process
positive regulation of immune response | positive regulation of cell killing | regulation of T cell mediated immunity | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | regulation of immune system process | regulation of T cell mediated cytotoxicity | regulation of leukocyte mediated cytotoxicity | cellular process | positive regulation of immune effector process | positive regulation of adaptive immune response | susceptibility to T cell mediated cytotoxicity | interspecies interaction between organisms | regulation of immune response | regulation of cellular process | cellular component organization | entry into host cell | viral life cycle | positive regulation of natural killer cell mediated immunity | response to stimulus | positive regulation of innate immune response | positive regulation of immune system process | susceptibility to natural killer cell mediated cytotoxicity | positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | adherens junction organization | viral entry into host cell | cell communication | viral process | regulation of innate immune response | regulation of adaptive immune response | cell adhesion | virus receptor activity | positive regulation of T cell mediated cytotoxicity | positive regulation of natural killer cell mediated cytotoxicity | cell-cell adhesion | positive regulation of T cell mediated immunity | regulation of natural killer cell mediated cytotoxicity | signaling | positive regulation of leukocyte mediated cytotoxicity | cell-cell adhesion via plasma-membrane adhesion molecules | regulation of natural killer cell mediated immunity | positive regulation of immune response to tumor cell | signal transduction | homophilic cell adhesion via plasma membrane adhesion molecules
GO Cellular Component
integral component of membrane | adherens junction | focal adhesion | cell | intrinsic component of membrane | cytoplasm | cell-substrate junction | cell-cell adherens junction | cell-cell junction | plasma membrane | extracellular region | extracellular space | cell periphery | cell-substrate adherens junction | cell surface | intracellular | cell junction | membrane
