QuickView for TAJ-alpha (gene)
- Gene Symbol:
- TNFRSF19
Homo sapiens - Full name:
- TNF receptor superfamily member 19
- Synonyms:
- TAJ, TAJ-alpha, TRADE, TROY, tumor necrosis factor receptor superfamily member 19, toxicity and JNK inducer
- Genomic Location:
- Chr 13: 23042723-23148232
- Description:
-
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, an...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
13q12.12
| Transcripts Names |
|---|
| NM_018647 |
| NM_148957 |
| NM_001204458 |
| NM_001204459 |
| XM_005266445 |
| XM_011535146 |
| NM_001354985 |
| XM_017020651 |
| XM_005266446 |
GO Molecular Function
transmembrane signaling receptor activity | death receptor activity | signaling receptor activity | tumor necrosis factor-activated receptor activity
GO Biological Process
molting cycle | response to cytokine | intracellular signal transduction | cellular response to tumor necrosis factor | positive regulation of phosphate metabolic process | cellular process | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cellular process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | positive regulation of cellular protein metabolic process | epithelium development | MAPK cascade | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | JNK cascade | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | programmed cell death | protein modification process | macromolecule modification | stress-activated protein kinase signaling cascade | regulation of cellular response to stress | apoptotic process | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | regulation of phosphorylation | cellular response to stress | death receptor activity | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | cellular response to cytokine stimulus | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | epidermis development | skin development | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | protein metabolic process | positive regulation of protein modification process | hair cycle | response to organic substance | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | hair cycle process | organic substance metabolic process | cell death | tumor necrosis factor-activated receptor activity | animal organ development | tumor necrosis factor-mediated signaling pathway | skin epidermis development | regulation of phosphate metabolic process | regulation of JNK cascade | positive regulation of MAPK cascade | regulation of stress-activated MAPK cascade | regulation of cell communication | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of phosphorylation | cellular protein metabolic process | developmental process | cellular protein modification process | positive regulation of metabolic process | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of signaling | hair follicle development | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | plasma membrane | cell periphery | intracellular | membrane
