QuickView for TALL-1 (gene)

Gene Symbol:

TNFSF13B Homo sapiens

Full name:

TNF superfamily member 13b

Synonyms:

BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4, tumor necrosis factor ligand superfamily member 13B, ApoL related ligand TALL-1, B-cell-activating factor, B-lymphocyte stimulator, Delta4 BAFF, TNF and ApoL-related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, delta BAFF, dendritic cell-derived TNF-like molecule, tumor necrosis factor (ligand) superfamily, member 13b, tumor necrosis factor (ligand) superfamily, member 20, tumor necrosis factor ligand 7A, tumor necrosis factor superfamily member 13b, tumor necrosis factor-like protein ZTNF4

Genomic Location:

Chr 13: 107719978-107757366

Description:

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the p...

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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

POU6F1_01 ,  IRF1_01 ,  CEBPA_01 ,  RYTTCCTG_ETS2_B ,  GATA_Q6 ,  CEBP_Q2_01 ,  CTTTGA_LEF1_Q2 ,  IRF1_Q6 ,  CEBPB_01 ,  LHX3_01 ,  LMO2COM_02 ,  IRF_Q6 ,  TAATTA_CHX10_01 ,  ICSBP_Q6 ,  ISRE_01 ,  STTTCRNTTT_IRF_Q6 ,  IRF2_01

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Cytogenetic Map:

13q33.3

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