Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for TANK (gene)


Gene Symbol:
TANK Homo sapiens Homo sapiens
Full name:
TRAF family member associated NFKB activator
Synonyms:
I-TRAF, ITRAF, TRAF2, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein
Genomic Location:
Chr 2: 161701712-161800928
Description:
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 2
2q24.2





GO Molecular Function

deubiquitinase activator activity | enzyme activator activity | cation binding | enzyme binding | peptidase activator activity | thiol-dependent ubiquitinyl hydrolase activity | hydrolase activity | cysteine-type peptidase activity | molecular function regulator | catalytic activity | ubiquitin-like protein ligase binding | thiol-dependent ubiquitin-specific protease activity | ion binding | protein binding | ubiquitinyl hydrolase activity | ubiquitin protein ligase binding | enzyme regulator activity | metal ion binding | peptidase activity

GO Biological Process

positive regulation of immune response | response to radiation | response to cytokine | response to interleukin-1 | deubiquitinase activator activity | immune response-regulating signaling pathway | intracellular signal transduction | enzyme activator activity | proteolysis | regulation of immune system process | negative regulation of cellular process | cellular response to tumor necrosis factor | innate immune response-activating signal transduction | cellular process | toll-like receptor signaling pathway | regulation of ubiquitin-specific protease activity | negative regulation of signaling | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | interspecies interaction between organisms | regulation of immune response | regulation of cellular process | regulation of metabolic process | peptidase activator activity | positive regulation of cellular protein metabolic process | thiol-dependent ubiquitinyl hydrolase activity | response to stimulus | positive regulation of innate immune response | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | activation of innate immune response | positive regulation of proteolysis | immune response-activating signal transduction | cysteine-type peptidase activity | molecular function regulator | nitrogen compound metabolic process | regulation of signal transduction | pattern recognition receptor signaling pathway | regulation of peptidase activity | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of protein deubiquitination | cellular response to stress | positive regulation of cellular metabolic process | cellular response to radiation | positive regulation of protein deubiquitination | regulation of nitrogen compound metabolic process | positive regulation of ubiquitin-specific protease activity | positive regulation of hydrolase activity | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | TRIF-dependent toll-like receptor signaling pathway | thiol-dependent ubiquitin-specific protease activity | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | viral process | positive regulation of molecular function | activation of immune response | protein metabolic process | positive regulation of protein modification process | response to organic substance | regulation of innate immune response | MyD88-independent toll-like receptor signaling pathway | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | organic substance metabolic process | cellular response to ionizing radiation | regulation of cell communication | negative regulation of signal transduction | signaling | I-kappaB kinase/NF-kappaB signaling | enzyme regulator activity | cellular response to interleukin-1 | positive regulation of metabolic process | immune system process | peptidase activity | response to tumor necrosis factor | cellular response to organic substance | regulation of I-kappaB kinase/NF-kappaB signaling | response to ionizing radiation | signal transduction | regulation of signaling | macromolecule metabolic process

GO Cellular Component

cell | cytoplasm | protein-containing complex | cytosol | intracellular