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QuickView for TEAD1 (gene)


Gene Symbol:
TEAD1 Homo sapiens Homo sapiens
Full name:
TEA domain transcription factor 1
Synonyms:
AA, NTEF-1, REF1, TCF-13, TCF13, TEAD-1, TEF-1, transcriptional enhancer factor TEF-1, TEA domain family member 1 (SV40 transcriptional enhancer factor), protein GT-IIC, transcription factor 13, transcriptional enhancer factor 1
Genomic Location:
Chr 11: 12652545-12922875
Description:
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
NFAT_Q4_01 NKX25_01 TGGAAA_NFAT_Q4_01 FOXJ2_02 NFAT_Q6 POU3F2_01 CATTGTYY_SOX9_B1 CTTTGCA_MIR527 TGTGTGA_MIR377 TTTGTAG_MIR520D
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-142-5p Predicted Gene Targets for miR-148 Predicted Gene Targets for miR-181 Predicted Gene Targets for miR-185 Predicted Gene Targets for miR-200b Predicted Gene Targets for miR-205 Predicted Gene Targets for miR-23 Predicted Gene Targets for miR-25 Predicted Gene Targets for miR-27 Predicted Gene Targets for miR-299
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 11
11p15.3


Transcripts Names
NM_021961
XM_940766
Protein Names
Q59EF3
E7EV65
A4FUP2
P28347



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcription coactivator binding | transcription factor recruiting activity | DNA binding | sequence-specific double-stranded DNA binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | double-stranded DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | protein dimerization activity | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription cofactor binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | intracellular signal transduction | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | hippo signaling | positive regulation of cellular metabolic process | regulation of pri-miRNA transcription by RNA polymerase II | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | positive regulation of pri-miRNA transcription by RNA polymerase II | cell communication | regulation of cellular metabolic process | regulation of RNA metabolic process | protein-containing complex assembly | DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | signaling | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | signal transduction | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | TEAD-1-YAP complex | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular