QuickView for TF2B (gene)

Gene Symbol:

GTF2B Homo sapiens

Full name:

general transcription factor IIB

Synonyms:

TF2B, TFIIB, transcription initiation factor IIB, RNA polymerase II transcription factor IIB, S300-II, general transcription factor TFIIB

Genomic Location:

Chr 1: 89090909-89129889

Description:

This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially ...

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This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  RYTTCCTG_ETS2_B ,  NKX3A_01 ,  AP1_Q6 ,  NFE2_01 ,  FOXO3_01 ,  AP1_01 ,  ETS2_B ,  STAT5A_03 ,  FOXO1_01 ,  BACH1_01 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  CTAGGAA_MIR384 ,  ETS1_B ,  AP1_Q4_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-384 ,  Predicted Gene Targets for miR-421

miRNA binding sites
(Source: miRecords):

[miR-122] Targeted Genes

Cytogenetic Map:

1p22.2

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