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QuickView for TF6 (gene)


Gene Symbol:
TFG Homo sapiens Homo sapiens
Full name:
TRK-fused gene
Synonyms:
HMSNP, SPG57, TF6, TRKT3, protein TFG, TRK-fused gene protein, TRKT3 oncogene
Genomic Location:
Chr 3: 101910850-101950501
Description:
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3q12.2





GO Molecular Function

identical protein binding | protein binding

GO Biological Process

establishment of localization | membrane organization | intracellular transport | cellular process | establishment of organelle localization | localization | establishment of localization in cell | vesicle targeting, to, from or within Golgi | regulation of cellular process | organelle localization | cellular component organization | COPII-coated vesicle budding | cellular localization | cellular component assembly | vesicle targeting | regulation of signal transduction | vesicle coating | positive regulation of intracellular signal transduction | vesicle-mediated transport | Golgi vesicle budding | establishment of vesicle localization | positive regulation of signal transduction | Golgi vesicle transport | protein-containing complex assembly | regulation of intracellular signal transduction | vesicle organization | vesicle budding from membrane | regulation of cell communication | ER to Golgi vesicle-mediated transport | positive regulation of I-kappaB kinase/NF-kappaB signaling | organelle organization | COPII vesicle coating | vesicle localization | regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of signaling | regulation of signaling

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | endomembrane system | Golgi membrane | membrane-bounded organelle | organelle | endoplasmic reticulum exit site | cytosol | intracellular | membrane