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QuickView for TF (gene)


Gene Symbol:
TF Homo sapiens Homo sapiens
Full name:
transferrin
Synonyms:
HEL-S-71p, PRO1557, PRO2086, TFQTL1, serotransferrin, beta-1 metal-binding globulin, epididymis secretory sperm binding protein Li 71p, siderophilin
Genomic Location:
Chr 3: 134947925-134980325
Description:
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticul...
Orthologs:
Mus musculus Rattus norvegicus Bos taurus Danio rerio Gallus gallus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3q22.1





GO Molecular Function

transition metal ion transmembrane transporter activity | ferric iron transmembrane transporter activity | ferric iron binding | cation binding | transmembrane transporter activity | ferrous iron binding | iron chaperone activity | iron ion binding | signaling receptor binding | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | ion binding | protein binding | iron ion transmembrane transporter activity | metal ion transmembrane transporter activity | metallochaperone activity | transition metal ion binding | transferrin receptor binding | inorganic cation transmembrane transporter activity | metal ion binding

GO Biological Process

regulation of JUN kinase activity | SMAD protein signal transduction | transition metal ion transmembrane transporter activity | ferric iron transmembrane transporter activity | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | actin filament-based process | exocytosis | positive regulation of cellular component organization | transferrin transport | iron ion transmembrane transport | intracellular signal transduction | regulation of localization | actin cytoskeleton organization | establishment of localization | myeloid cell differentiation | platelet degranulation | regulation of MAP kinase activity | response to metal ion | cell differentiation | cellular chemical homeostasis | cellular response to iron ion | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | membrane organization | tissue homeostasis | regulation of bone remodeling | positive regulation of cellular biosynthetic process | cellular process | secretion | regulation of cell motility | localization | cellular homeostasis | protein transport | metal ion transport | immune system development | positive regulation of protein kinase activity | macromolecule localization | transition metal ion transport | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | anatomical structure homeostasis | regulation of cellular process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | transmembrane transporter activity | positive regulation of cellular protein metabolic process | cellular component organization | MAPK cascade | regulation of iron ion import | cellular response to metal ion | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | JNK cascade | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | multicellular organismal homeostasis | supramolecular fiber organization | cellular response to inorganic substance | secretion by cell | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | hemopoiesis | protein modification process | response to iron ion | macromolecule modification | activation of protein kinase activity | metal ion homeostasis | stress-activated protein kinase signaling cascade | regulation of nucleic acid-templated transcription | leukocyte differentiation | regulation of cellular response to stress | system development | nitrogen compound metabolic process | regulation of signal transduction | regulation of protein stability | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | actin filament organization | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | ion transmembrane transport | regulation of receptor-mediated endocytosis | positive regulation of receptor-mediated endocytosis | regulation of gene expression | osteoclast differentiation | organic substance transport | cellular response to stress | cation transmembrane transporter activity | myeloid leukocyte differentiation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of JNK cascade | peptide transport | positive regulation of intracellular signal transduction | vesicle-mediated transport | regulation of cellular component movement | ion transmembrane transporter activity | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | regulated exocytosis | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | ferric iron transport | homeostatic process | regulation of protein phosphorylation | regulation of locomotion | iron ion homeostasis | regulation of RNA metabolic process | positive regulation of transport | positive regulation of molecular function | activation of MAPK activity | cation transmembrane transport | protein metabolic process | iron ion transmembrane transporter activity | positive regulation of protein modification process | regulation of kinase activity | metal ion transmembrane transporter activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | regulation of bone resorption | regulation of tissue remodeling | amide transport | regulation of vesicle-mediated transport | chemical homeostasis | organic substance metabolic process | animal organ development | retina homeostasis | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | cytoskeleton organization | inorganic cation transmembrane transport | cellular iron ion homeostasis | establishment of protein localization | regulation of JNK cascade | positive regulation of MAPK cascade | regulation of stress-activated MAPK cascade | regulation of cell communication | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | regulation of transcription, DNA-templated | regulation of endocytosis | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | cation transport | positive regulation of MAP kinase activity | iron ion transport | positive regulation of tissue remodeling | regulation of ion transport | developmental process | organelle organization | cellular protein modification process | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of bone resorption | positive regulation of nucleic acid-templated transcription | cellular metal ion homeostasis | ERK1 and ERK2 cascade | positive regulation of JUN kinase activity | positive regulation of metabolic process | ion transport | transition metal ion homeostasis | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | activation of JUN kinase activity | positive regulation of cell motility | positive regulation of endocytosis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | post-translational protein modification | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | basal plasma membrane | intracellular membrane-bounded organelle | late endosome | apical plasma membrane | extrinsic component of membrane | clathrin-coated vesicle membrane | organelle membrane | clathrin-coated vesicle | cytoplasmic vesicle | basal part of cell | cell | plasma membrane protein complex | extrinsic component of plasma membrane | HFE-transferrin receptor complex | cytoplasmic vesicle lumen | external side of plasma membrane | cytoplasm | intracellular organelle | receptor complex | endoplasmic reticulum | apical part of cell | endosome membrane | protein-containing complex | recycling endosome | secretory vesicle | endomembrane system | plasma membrane | vesicle | endoplasmic reticulum lumen | perinuclear region of cytoplasm | clathrin-coated pit | extracellular exosome | endosome | extracellular region | coated vesicle membrane | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | extracellular space | cell periphery | extrinsic component of external side of plasma membrane | membrane-enclosed lumen | early endosome | basolateral plasma membrane | secretory granule lumen | blood microparticle | intracellular vesicle | cell surface | endocytic vesicle | intracellular | membrane | vesicle lumen | cytoplasmic vesicle membrane | coated vesicle