QuickView for TFE (gene)
- Gene Symbol:
- Tcf4
Mus musculus - Full name:
- transcription factor 4
- Synonyms:
- 5730422P05Rik, ASP-I2, E2-2, E2.2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, SEF-2, SEF2, SEF2-1, TFE, Tcf-4, bHLHb19, transcription factor 4, MITF-2, SL3-3 enhancer factor 2, Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2), class A helix-loop-helix transcription factor ME2, immunoglobulin transcription factor-2
- Genomic Location:
- Chr 18: 69504175-69843998
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
| Protein Names |
|---|
| Q60721 |
| A0A0J9YUG4 |
| Q60722 |
| Q64072 |
| Q91XK1 |
| Q8BPX7 |
| Q91YV0 |
| A0A0J9YTR9 |
| A0A0J9YUZ0 |
| Q80UE8 |
| Q62211 |
| A0A0J9YTU7 |
GO Molecular Function
sequence-specific DNA binding | protein self-association | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | TFIIB-class transcription factor binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | chromatin binding | RNA polymerase II regulatory region DNA binding | E-box binding | bHLH transcription factor binding | DNA binding | sequence-specific double-stranded DNA binding | transcription corepressor activity | identical protein binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting | transcription factor binding | RNA polymerase II transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription coregulator activity | basal RNA polymerase II transcription machinery binding | heterocyclic compound binding | protein C-terminus binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | regulation of neurogenesis | regulation of cell development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | neurogenesis | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of angiogenesis | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | regulation of vascular endothelial growth factor signaling pathway | regulation of vasculature development | cellular nitrogen compound biosynthetic process | negative regulation of angiogenesis | protein-DNA complex assembly | cellular nitrogen compound metabolic process | endothelial cell activation | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of neuron differentiation | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | transcription corepressor activity | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | biosynthetic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | regulation of cellular metabolic process | regulation of RNA metabolic process | regulation of cellular response to growth factor stimulus | protein-containing complex assembly | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting | anatomical structure development | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | cell activation | regulation of cell communication | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | negative regulation of vasculature development | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | positive regulation of neuron differentiation | cellular metabolic process | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
nuclear transcription factor complex | chromosome | catenin-TCF7L2 complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | chromatin | nuclear chromosome | beta-catenin-TCF7L2 complex | beta-catenin-TCF complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular
