QuickView for TFIIE-B (gene)
- Gene Symbol:
- GTF2E2
Homo sapiens - Full name:
- general transcription factor IIE subunit 2
- Synonyms:
- FE, TF2E2, TFIIE-B, TTD6, transcription initiation factor IIE subunit beta, TFIIE beta subunit, TFIIE-beta, general transcription factor IIE, polypeptide 2, beta 34kDa
- Genomic Location:
- Chr 8: 30555573-30635280
- Description:
-
The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
8p12
| Transcripts Names |
|---|
| NM_002095 |
| XM_017013363 |
| XM_011544509 |
| XM_011544510 |
| XM_017013364 |
| XM_024447138 |
| NM_001348353 |
GO Molecular Function
transcription factor activity, transcription factor binding | transcription factor activity, RNA polymerase II transcription factor binding | nucleic acid binding | TFIIH-class transcription factor binding | DNA binding | organic cyclic compound binding | protein binding | transcription factor binding | RNA polymerase II transcription factor binding | basal RNA polymerase II transcription machinery binding | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | transcription factor activity, transcription factor binding | snRNA metabolic process | cellular process | snRNA transcription | transcription factor activity, RNA polymerase II transcription factor binding | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | snRNA transcription by RNA polymerase II | cellular nitrogen compound metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | ncRNA transcription | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | ncRNA metabolic process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
nuclear transcription factor complex | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | nuclear speck | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | transcription factor TFIIE complex | cytosol | intracellular | RNA polymerase II, holoenzyme
