QuickView for TFPI-2 (gene)

Gene Symbol:

TFPI2 Homo sapiens

Full name:

tissue factor pathway inhibitor 2

Synonyms:

PP5, REF1, TFPI-2, tissue factor pathway inhibitor 2, placental protein 5, retinal pigment epithelium cell factor 1

Genomic Location:

Chr 7: 93353678-93358001

Description:

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing result...

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This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  GGGAGGRR_MAZ_Q6 ,  GGGCGGR_SP1_Q6 ,  NRF2_Q4 ,  AATGTGA_MIR23A_MIR23B

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-323

Cytogenetic Map:

7q21.3

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