QuickView for TGFAA (gene)
- Gene Symbol:
- Tgfa
Rattus norvegicus - Full name:
- transforming growth factor alpha
- Synonyms:
- RATTGFAA, TGFAA, protransforming growth factor alpha
- Genomic Location:
- Chr 4: 120355649-120437774
- Description:
-
acts as an EGF receptor ligand; inhibits apoptosis that results from epithelial detachment from the extracellular matrix
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Canis lupus familiaris , Gallus gallus , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
signaling receptor binding | molecular function regulator | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | epidermal growth factor receptor binding | growth factor receptor binding
GO Biological Process
regulation of cell cycle process | positive regulation of cellular component organization | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | negative regulation of cellular process | regulation of MAP kinase activity | positive regulation of epithelial cell proliferation | positive regulation of signaling receptor activity | response to drug | positive regulation of phosphate metabolic process | regulation of organelle organization | blood vessel morphogenesis | cellular process | positive regulation of epidermal growth factor-activated receptor activity | regulation of mitotic nuclear division | positive regulation of protein kinase activity | negative regulation of apoptotic process | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | hepaticobiliary system development | epidermal growth factor receptor signaling pathway | positive regulation of cellular protein metabolic process | regulation of cell division | response to stimulus | vasculature development | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | gland morphogenesis | response to stress | regulation of cell proliferation | tube morphogenesis | cardiovascular system development | ERBB signaling pathway | positive regulation of protein serine/threonine kinase activity | activation of protein kinase activity | positive regulation of ERBB signaling pathway | molecular function regulator | blood vessel development | regulation of protein tyrosine kinase activity | system development | regulation of signal transduction | positive regulation of organelle organization | hepatocyte proliferation | multicellular organism development | regulation of MAPK cascade | mammary gland development | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | liver morphogenesis | wound healing | positive regulation of cell cycle | mammary gland lobule development | positive regulation of mitotic cell cycle | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | liver development | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | cell proliferation | regulation of cellular protein metabolic process | angiogenesis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of mitotic cell cycle | positive regulation of molecular function | activation of MAPK activity | regulation of signaling receptor activity | regulation of epidermal growth factor-activated receptor activity | receptor regulator activity | positive regulation of protein modification process | gland development | epithelial cell proliferation | regulation of kinase activity | response to wounding | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | negative regulation of programmed cell death | receptor ligand activity | regulation of epidermal growth factor receptor signaling pathway | animal organ development | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of MAPK cascade | mammary gland alveolus development | anatomical structure formation involved in morphogenesis | regulation of cell communication | signaling | regulation of ERBB signaling pathway | regulation of epithelial cell proliferation | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | positive regulation of epidermal growth factor receptor signaling pathway | anatomical structure morphogenesis | positive regulation of MAP kinase activity | developmental process | positive regulation of cell cycle process | tube development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | regulation of cell death | negative regulation of cell death | circulatory system development | regulation of cellular component organization | positive regulation of signaling | positive regulation of mitotic nuclear division | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | plasma membrane | vesicle | perinuclear region of cytoplasm | integral component of plasma membrane | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cell periphery | basolateral plasma membrane | intracellular vesicle | cell surface | intracellular | membrane | intrinsic component of plasma membrane
