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QuickView for TIAL1 (gene)


Gene Symbol:
TIAL1 Homo sapiens Homo sapiens
Full name:
TIA1 cytotoxic granule associated RNA binding protein like 1
Synonyms:
TCBP, TIAR, nucleolysin TIAR, T-cluster binding protein, TIA-1-related nucleolysin, aging-associated gene 7 protein
Genomic Location:
Chr 10: 121322967-121346531
Description:
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, enc...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Gallus gallus Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
HNF4ALPHA_Q6 SMTTTTGT_UNKNOWN AP1_C TGANTCA_AP1_C TTANTCA_UNKNOWN RYTTCCTG_ETS2_B MAZ_Q6 NFAT_Q6 MYC_Q2 GATA_Q6
Cytogenetic Map:
chr 10
10q26.11





GO Molecular Function

nucleic acid binding | DNA binding | AU-rich element binding | organic cyclic compound binding | heterocyclic compound binding | RNA binding

GO Biological Process

developmental process involved in reproduction | cell differentiation | defense response | cellular process | multicellular organismal reproductive process | response to growth factor | gamete generation | regulation of cellular process | regulation of metabolic process | response to stimulus | cellular response to fibroblast growth factor stimulus | response to stress | germ cell development | regulation of cell proliferation | programmed cell death | reproduction | regulation of nucleic acid-templated transcription | apoptotic process | reproductive process | fibroblast growth factor receptor signaling pathway | regulation of gene expression | stem cell division | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | regulation of transcription by RNA polymerase II | cell division | cell communication | regulation of cellular metabolic process | positive regulation of cell proliferation | regulation of RNA metabolic process | multicellular organism reproduction | response to organic substance | anatomical structure development | cell surface receptor signaling pathway | regulation of RNA biosynthetic process | cell death | signaling | regulation of transcription, DNA-templated | cell development | developmental process | response to fibroblast growth factor | transmembrane receptor protein tyrosine kinase signaling pathway | cellular response to organic substance | sexual reproduction | signal transduction | cellular response to growth factor stimulus | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cytoplasmic stress granule | cell | nuclear lumen | ribonucleoprotein granule | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | vacuole | ribonucleoprotein complex | lytic vacuole | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | lysosome | membrane-enclosed lumen | intracellular