QuickView for TIN-AG (gene)
- Gene Symbol:
- TINAG
Homo sapiens - Full name:
- tubulointerstitial nephritis antigen
- Synonyms:
- TIN-AG, tubulointerstitial nephritis antigen
- Genomic Location:
- Chr 6: 54281162-54362872
- Description:
-
This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ont...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
6p12.1
| Transcripts Names |
|---|
| NM_014464 |
| XM_011514497 |
| XR_001743344 |
| XM_017010748 |
| XM_017010747 |
| XM_017010746 |
| XM_017010745 |
| XM_006715062 |
GO Molecular Function
nucleotide binding | hydrolase activity | cysteine-type peptidase activity | catalytic activity | organic cyclic compound binding | cysteine-type endopeptidase activity | carbohydrate binding | scavenger receptor activity | endopeptidase activity | heterocyclic compound binding | cargo receptor activity | peptidase activity | small molecule binding | polysaccharide binding
GO Biological Process
proteolysis | establishment of localization | cellular process | organic substance catabolic process | localization | proteolysis involved in cellular protein catabolic process | catabolic process | response to stimulus | cellular protein catabolic process | cysteine-type peptidase activity | nitrogen compound metabolic process | protein catabolic process | vesicle-mediated transport | cysteine-type endopeptidase activity | scavenger receptor activity | protein metabolic process | import into cell | cellular macromolecule catabolic process | metabolic process | endocytosis | cell adhesion | immune response | organic substance metabolic process | organonitrogen compound catabolic process | endopeptidase activity | cellular protein metabolic process | receptor-mediated endocytosis | cargo receptor activity | immune system process | cellular metabolic process | peptidase activity | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | extracellular matrix | basement membrane | cell | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | vacuole | lytic vacuole | extracellular region | membrane-bounded organelle | organelle | lysosome | extracellular space | intracellular
