QuickView for TIN1 (gene)
- Gene Symbol:
- TNKS
Homo sapiens - Full name:
- tankyrase
- Synonyms:
- ARTD5, PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1, pART5, tankyrase-1, ADP-ribosyltransferase diphtheria toxin-like 5, TANK1, TNKS-1, TRF1-interacting ankyrin-related ADP-ribose polymerase 1, poly [ADP-ribose] polymerase 5A, tankyrase I, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
- Genomic Location:
- Chr 8: 9450855-9677266
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
8p23.1
GO Molecular Function
NAD+ ADP-ribosyltransferase activity | cation binding | catalytic activity | transferase activity, transferring glycosyl groups | ion binding | protein binding | zinc ion binding | transferase activity, transferring pentosyl groups | transferase activity | histone binding | transition metal ion binding | metal ion binding
GO Biological Process
regulation of telomere maintenance via telomerase | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | microtubule cytoskeleton organization involved in mitosis | positive regulation of cellular component organization | positive regulation of telomere capping | peptidyl-amino acid modification | establishment of localization | negative regulation of cellular process | microtubule cytoskeleton organization | regulation of organelle organization | negative regulation of DNA metabolic process | microtubule-based process | regulation of chromosome segregation | positive regulation of cellular biosynthetic process | cellular process | localization | protein transport | regulation of mitotic nuclear division | positive regulation of telomerase activity | macromolecule localization | negative regulation of chromosome segregation | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | spindle assembly | negative regulation of cellular metabolic process | regulation of binding | regulation of cellular process | regulation of metabolic process | cellular component organization | regulation of telomere capping | response to stimulus | peptidyl-threonine phosphorylation | mitotic spindle organization | cellular localization | regulation of DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | protein modification process | macromolecule modification | cell-cell signaling | positive regulation of telomere maintenance via telomere lengthening | negative regulation of maintenance of mitotic sister chromatid cohesion | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | organelle assembly | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | Wnt signaling pathway | protein auto-ADP-ribosylation | phosphorus metabolic process | regulation of telomere maintenance | regulation of catalytic activity | positive regulation of chromosome organization | regulation of gene expression | organic substance transport | cell cycle | positive regulation of cellular metabolic process | regulation of telomerase activity | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | peptide transport | negative regulation of DNA binding | regulation of transcription by RNA polymerase II | protein localization to organelle | negative regulation of binding | negative regulation of mitotic nuclear division | cell division | mRNA transport | phosphorylation | establishment of RNA localization | positive regulation of telomere maintenance via telomerase | protein phosphorylation | phosphate-containing compound metabolic process | regulation of telomere maintenance via telomere lengthening | cell communication | regulation of cellular metabolic process | negative regulation of mitotic sister chromatid segregation | positive regulation of DNA biosynthetic process | positive regulation of signal transduction | negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric | regulation of RNA metabolic process | negative regulation of telomere maintenance | regulation of mitotic cell cycle | positive regulation of molecular function | protein polyubiquitination | regulation of sister chromatid cohesion | protein metabolic process | protein poly-ADP-ribosylation | protein ubiquitination | protein localization to chromosome, telomeric region | regulation of sister chromatid segregation | protein ADP-ribosylation | nucleobase-containing compound transport | mitotic cell cycle | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | negative regulation of mitotic cell cycle | cellular protein localization | amide transport | organic substance metabolic process | negative regulation of sister chromatid cohesion | protein modification by small protein conjugation or removal | regulation of Wnt signaling pathway | cytoskeleton organization | regulation of chromosome organization | establishment of protein localization | negative regulation of telomeric DNA binding | RNA transport | positive regulation of canonical Wnt signaling pathway | negative regulation of cell cycle | regulation of mitotic sister chromatid segregation | regulation of cell communication | negative regulation of chromosome organization | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | negative regulation of telomere maintenance via telomere lengthening | protein localization | cellular protein metabolic process | cellular macromolecule localization | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | organelle organization | regulation of DNA biosynthetic process | peptidyl-serine phosphorylation | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | positive regulation of Wnt signaling pathway | cellular metabolic process | negative regulation of cell cycle process | spindle organization | RNA localization | regulation of cellular component organization | positive regulation of signaling | protein localization to chromosome | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
chromosome | pericentriolar material | intracellular membrane-bounded organelle | organelle membrane | microtubule organizing center | nuclear membrane | chromosome, centromeric region | cell | nuclear lumen | cytoplasm | spindle | intracellular organelle | nuclear body | centrosome | Golgi apparatus | protein-containing complex | endomembrane system | nucleoplasm | nuclear envelope | nuclear chromosome | microtubule cytoskeleton | spindle pole | chromosome, telomeric region | Golgi membrane | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear pore | cytosol | cytoskeleton | nuclear chromosome, telomeric region | mitotic spindle pole | intracellular | mitotic spindle | membrane
