Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for TIP-2 (gene)


Gene Symbol:
GIPC1 Homo sapiens Homo sapiens
Full name:
GIPC PDZ domain containing family member 1
Synonyms:
C19orf3, GIPC, GLUT1CBP, Hs.6454, IIP-1, NIP, RGS19IP1, SEMCAP, SYNECTIIN, SYNECTIN, TIP-2, PDZ domain-containing protein GIPC1, GAIP C-terminus-interacting protein, GLUT1 C-terminal binding protein, IGF-1 receptor interacting protein 1, RGS-GAIP-interacting protein, RGS19-interacting protein 1, regulator of G-protein signalling 19 interacting protein 1, tax interaction protein 2
Genomic Location:
Chr 19: 14449571-14467944
Description:
GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 19
19p13.12





GO Molecular Function

actin binding | cadherin binding | signaling receptor binding | myosin binding | protein domain specific binding | cytoskeletal protein binding | identical protein binding | cell adhesion molecule binding | protein binding | protein homodimerization activity | protein dimerization activity | PDZ domain binding

GO Biological Process

regulation of cell cycle process | cell motility | establishment of localization | regulation of transforming growth factor beta receptor signaling pathway | negative regulation of cellular process | epithelial cell migration | intracellular transport | negative regulation of proteolysis | cellular process | secretion | localization | negative regulation of ubiquitin-dependent protein catabolic process | protein transport | chemical synaptic transmission | dicarboxylic acid transport | epithelium migration | anion transport | macromolecule localization | regulation of proteolysis | regulation of cell cycle | positive regulation of cell division | establishment of localization in cell | negative regulation of cellular metabolic process | positive regulation of cytokinesis | regulation of cellular process | regulation of metabolic process | regulation of cell division | negative regulation of cellular protein catabolic process | response to stimulus | acid secretion | regulation of cellular protein catabolic process | intracellular protein transport | endothelial cell migration | cellular localization | secretion by cell | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | modulation of chemical synaptic transmission | cell-cell signaling | locomotion | regulation of signal transduction | regulation of protein stability | cell migration | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | positive regulation of cell cycle | organic substance transport | synaptic signaling | regulation of nitrogen compound metabolic process | peptide transport | organic acid transport | regulation of cellular protein metabolic process | organic anion transport | cell communication | regulation of cellular metabolic process | regulation of cytokinesis | regulation of protein metabolic process | positive regulation of signal transduction | regulation of cellular response to growth factor stimulus | amino acid transport | regulation of proteasomal ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | regulation of proteasomal protein catabolic process | cellular protein localization | amide transport | negative regulation of cellular protein metabolic process | establishment of protein localization | negative regulation of protein catabolic process | negative regulation of protein metabolic process | positive regulation of transforming growth factor beta receptor signaling pathway | regulation of cell communication | signaling | protein localization | carboxylic acid transport | cellular macromolecule localization | glutamate secretion | positive regulation of cell cycle process | regulation of synaptic plasticity | protein targeting | ion transport | ameboidal-type cell migration | regulation of ubiquitin-dependent protein catabolic process | negative regulation of proteolysis involved in cellular protein catabolic process | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | negative regulation of proteasomal protein catabolic process

GO Cellular Component

brush border | dendritic spine | exocytic vesicle | dendrite | synapse | neuron projection | somatodendritic compartment | organelle membrane | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | dendritic tree | presynapse | cell projection | secretory vesicle | endomembrane system | neuron spine | postsynapse | vesicle | transport vesicle | extracellular exosome | cytoplasmic region | synaptic vesicle | extracellular region | cell cortex | membrane-bounded organelle | extracellular vesicle | dendritic shaft | organelle | vesicle membrane | extracellular space | cell periphery | cytosol | intracellular vesicle | endocytic vesicle | intracellular | membrane