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QuickView for TIR8 (gene)


Gene Symbol:
SIGIRR Homo sapiens Homo sapiens
Full name:
single Ig and TIR domain containing
Synonyms:
IL-1R8, TIR8, single Ig IL-1-related receptor, interleukin-1 receptor 8 long isoform, single Ig IL-1R-related molecule, single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, single immunoglobulin domain IL1R1 related, single immunoglobulin domain-containing IL1R-related protein, toll/interleukin-1 receptor 8
Genomic Location:
Chr 11: 395716-407397
Orthologs:
Mus musculus Rattus norvegicus Gallus gallus Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11p15.5





GO Molecular Function

protein binding

GO Biological Process

response to cytokine | negative regulation of cellular process | defense response | cellular process | regulation of cytokine biosynthetic process | negative regulation of signaling | regulation of response to cytokine stimulus | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | response to stimulus | response to stress | negative regulation of metabolic process | regulation of nucleic acid-templated transcription | regulation of signal transduction | regulation of gene expression | negative regulation of chemokine production | negative regulation of cytokine production | regulation of nitrogen compound metabolic process | negative regulation of DNA-binding transcription factor activity | acute-phase response | cellular response to cytokine stimulus | negative regulation of cytokine biosynthetic process | cell communication | regulation of cellular metabolic process | inflammatory response | regulation of protein metabolic process | regulation of cytokine-mediated signaling pathway | regulation of RNA metabolic process | response to organic substance | regulation of lipopolysaccharide-mediated signaling pathway | regulation of DNA-binding transcription factor activity | negative regulation of response to cytokine stimulus | regulation of RNA biosynthetic process | negative regulation of biosynthetic process | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | regulation of cytokine production | regulation of chemokine production | negative regulation of cytokine-mediated signaling pathway | acute inflammatory response | negative regulation of lipopolysaccharide-mediated signaling pathway | cellular response to organic substance | negative regulation of chemokine biosynthetic process | signal transduction | regulation of signaling

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | cell periphery | membrane