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QuickView for TNC;jsessionid=DF3FB09F3D48514796170E68146687DE (gene)


Gene Symbol:
TNC Homo sapiens Homo sapiens
Full name:
tenascin C
Synonyms:
150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C, tenascin, GP 150-225, cytotactin, deafness, autosomal dominant 56, glioma-associated-extracellular matrix antigen, hexabrachion (tenascin), myotendinous antigen, neuronectin, tenascin-C additional domain 1, tenascin-C isoform 14/AD1/16
Genomic Location:
Chr 9: 116822626-116920307
Description:
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, a...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 9
9q33.1





GO Molecular Function

structural molecule activity | proteoglycan binding | syndecan binding | carbohydrate derivative binding | protein binding | extracellular matrix structural constituent

GO Biological Process

response to extracellular stimulus | response to nutrient levels | extracellular structure organization | developmental process involved in reproduction | mesenchymal-epithelial cell signaling | morphogenesis of an epithelium | response to hormone | negative regulation of cellular process | cell differentiation | respiratory tube development | nervous system development | cellular response to extracellular stimulus | response to drug | neurogenesis | generation of neurons | response to antibiotic | cellular process | cellular response to prostaglandin D stimulus | epithelial tube morphogenesis | odontogenesis | developmental growth | neuron development | reproductive system development | response to growth factor | tissue development | response to prostaglandin | cellular response to retinoic acid | regeneration | regulation of cellular process | cellular response to lipid | regulation of metabolic process | cellular response to prostaglandin stimulus | epithelium development | cellular component organization | prostate gland epithelium morphogenesis | epithelial tube branching involved in lung morphogenesis | urogenital system development | response to stimulus | respiratory system development | negative regulation of cell adhesion | gland morphogenesis | response to stress | cellular response to vitamin | regulation of cell proliferation | tube morphogenesis | reproduction | response to alcohol | axis elongation | extracellular matrix organization | cellular response to organic cyclic compound | response to vitamin D | protein modification process | regulation of cell adhesion | macromolecule modification | cell-cell signaling | response to ethanol | cellular response to hormone stimulus | system development | cellular response to nutrient levels | cellular response to vitamin D | nitrogen compound metabolic process | reproductive process | multicellular organism development | response to fatty acid | wound healing | regulation of gene expression | axon development | response to ketone | cellular response to stress | response to lipid | mesenchymal-epithelial cell signaling involved in prostate gland development | neuromuscular junction development | response to axon injury | animal organ morphogenesis | response to nutrient | synapse organization | neuron projection regeneration | response to toxic substance | cell communication | odontogenesis of dentin-containing tooth | peripheral nervous system axon regeneration | positive regulation of cell proliferation | response to retinoic acid | cellular response to fatty acid | bud outgrowth involved in lung branching | neuron differentiation | protein metabolic process | cellular response to nutrient | response to organic substance | gland development | tissue morphogenesis | branching morphogenesis of an epithelial tube | response to wounding | response to mechanical stimulus | anatomical structure development | developmental growth involved in morphogenesis | branch elongation of an epithelium | cell projection organization | metabolic process | cell adhesion | neuron projection development | organic substance metabolic process | response to vitamin | animal organ development | prostate gland morphogenesis | lung development | morphogenesis of a branching epithelium | signaling | response to organic cyclic compound | cell development | cellular protein metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | reproductive structure development | axon regeneration | developmental process | cellular protein modification process | tube development | response to fibroblast growth factor | lung morphogenesis | positive regulation of metabolic process | ossification | osteoblast differentiation | cellular metabolic process | cellular response to organic substance | positive regulation of gene expression | post-translational protein modification | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | extracellular matrix | basement membrane | adherens junction | focal adhesion | cell | cytoplasm | collagen-containing extracellular matrix | cell-substrate junction | intracellular organelle | endoplasmic reticulum | endomembrane system | endoplasmic reticulum lumen | interstitial matrix | extracellular region | membrane-bounded organelle | organelle | extracellular space | membrane-enclosed lumen | cell-substrate adherens junction | intracellular | cell junction | membrane