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QuickView for TNF-R55 (gene)


Gene Symbol:
TNFRSF1A Homo sapiens Homo sapiens
Full name:
TNF receptor superfamily member 1A
Synonyms:
CD120a, FPF, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60, tumor necrosis factor receptor superfamily member 1A, TNF-R1, TNF-RI, TNFR-I, tumor necrosis factor binding protein 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor type 1, tumor necrosis factor-alpha receptor
Genomic Location:
Chr 12: 6308184-6321522
Description:
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Danio rerio Gallus gallus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 12
12p13.31





GO Molecular Function

cytokine binding | transmembrane signaling receptor activity | tumor necrosis factor binding | death receptor activity | signaling receptor activity | identical protein binding | protein binding | tumor necrosis factor-activated receptor activity

GO Biological Process

regulation of muscle system process | positive regulation of macromolecule biosynthetic process | response to cytokine | protein localization to cell periphery | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell development | regulation of localization | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | defense response to other organism | negative regulation of cellular process | positive regulation of developmental process | cellular response to tumor necrosis factor | defense response | intrinsic apoptotic signaling pathway in response to DNA damage | regulation of extracellular matrix organization | positive regulation of sphingolipid biosynthetic process | pulmonary valve development | positive regulation of phosphate metabolic process | positive regulation of cellular biosynthetic process | cellular process | negative regulation of inflammatory response | localization | extrinsic apoptotic signaling pathway | macromolecule localization | regulation of response to cytokine stimulus | negative regulation of secretion | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | interspecies interaction between organisms | intrinsic apoptotic signaling pathway | negative regulation of muscle hypertrophy | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | cellular lipid metabolic process | regulation of ceramide biosynthetic process | response to stimulus | cellular response to mechanical stimulus | monocarboxylic acid metabolic process | regulation of peptidyl-tyrosine phosphorylation | negative regulation of extracellular matrix organization | positive regulation of protein metabolic process | response to stress | positive regulation of JAK-STAT cascade | positive regulation of lipid biosynthetic process | regulation of epithelial cell differentiation | programmed cell death | cellular localization | negative regulation of transport | extrinsic apoptotic signaling pathway via death domain receptors | positive regulation of RNA biosynthetic process | cellular component assembly | regulation of nucleic acid-templated transcription | apoptotic process | response to external biotic stimulus | system development | regulation of signal transduction | negative regulation of secretion by cell | multicellular organism development | positive regulation of inflammatory response | cellular response to DNA damage stimulus | lipid metabolic process | regulation of phosphorylation | protein localization to plasma membrane | regulation of gene expression | protein localization to membrane | cellular response to stress | death receptor activity | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | negative regulation of cardiac muscle hypertrophy | regulation of nitrogen compound metabolic process | small molecule metabolic process | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | negative regulation of extracellular matrix constituent secretion | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | response to bacterium | death-inducing signaling complex assembly | cell communication | regulation of cellular metabolic process | positive regulation of tyrosine phosphorylation of STAT protein | regulation of establishment of endothelial barrier | semi-lunar valve development | inflammatory response | regulation of tumor necrosis factor-mediated signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | heart development | defense response to bacterium | regulation of protein phosphorylation | regulation of cytokine-mediated signaling pathway | regulation of RNA metabolic process | viral process | regulation of lipid biosynthetic process | apoptotic signaling pathway | positive regulation of apoptotic process involved in development | carboxylic acid metabolic process | protein-containing complex assembly | heart valve development | regulation of cardiac muscle hypertrophy | positive regulation of protein modification process | response to organic substance | regulation of JAK-STAT cascade | response to mechanical stimulus | positive regulation of ceramide biosynthetic process | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | cellular protein localization | prostaglandin metabolic process | regulation of secretion | positive regulation of cell death | organic substance metabolic process | cell death | tumor necrosis factor-activated receptor activity | animal organ development | positive regulation of programmed cell death | tumor necrosis factor-mediated signaling pathway | regulation of phosphate metabolic process | fatty acid metabolic process | regulation of sphingolipid biosynthetic process | icosanoid metabolic process | regulation of cell communication | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | I-kappaB kinase/NF-kappaB signaling | protein localization | organic acid metabolic process | positive regulation of phosphorylation | cellular macromolecule localization | response to biotic stimulus | regulation of developmental process | developmental process | regulation of transport | positive regulation of transcription, DNA-templated | aortic valve development | regulation of endothelial cell differentiation | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | regulation of apoptotic process involved in development | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | cellular metabolic process | response to tumor necrosis factor | positive regulation of apoptotic process involved in morphogenesis | cellular response to organic substance | regulation of cell death | circulatory system development | regulation of inflammatory response | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | membrane microdomain | Golgi apparatus | protein-containing complex | endomembrane system | plasma membrane | membrane raft | mitochondrion | integral component of plasma membrane | Golgi membrane | extracellular region | membrane-bounded organelle | organelle | extracellular space | cell periphery | cell surface | intracellular | membrane | intrinsic component of plasma membrane