QuickView for TNFRSF6B (gene)
- Gene Symbol:
- TNFRSF6B
Homo sapiens - Full name:
- TNF receptor superfamily member 6b
- Synonyms:
- DCR3, DJ583P15.1.1, M68, M68E, TR6, tumor necrosis factor receptor superfamily member 6B, decoy receptor 3 variant 1, decoy receptor 3 variant 2, decoy receptor for Fas ligand, tumor necrosis factor receptor superfamily, member 6b, decoy
- Genomic Location:
- Chr 20: 61796732-61800481
- Description:
-
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-thr...
- Orthologs:
- Gallus gallus , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
20q13.33
GO Molecular Function
signaling receptor activity | protein binding
GO Biological Process
response to cytokine | regulation of programmed cell death | negative regulation of cellular process | cellular response to tumor necrosis factor | cellular process | negative regulation of apoptotic process | regulation of cellular process | regulation of apoptotic process | response to stimulus | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | cell communication | response to organic substance | cell surface receptor signaling pathway | negative regulation of programmed cell death | tumor necrosis factor-mediated signaling pathway | signaling | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | negative regulation of cell death | signal transduction
