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QuickView for TNKS2;jsessionid=6491F9A340308A3D4F4AAB5E86001C19 (gene)


Gene Symbol:
TNKS2 Homo sapiens Homo sapiens
Full name:
tankyrase 2
Synonyms:
ARTD6, PARP-5b, PARP-5c, PARP5B, PARP5C, TANK2, TNKL, pART6, tankyrase-2, ADP-ribosyltransferase diphtheria toxin-like 6, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, poly [ADP-ribose] polymerase 5B, tankyrase II, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, tankyrase-like protein, tankyrase-related protein
Genomic Location:
Chr 10: 93548049-93615012
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 10
10q23.32





GO Molecular Function

NAD+ ADP-ribosyltransferase activity | cation binding | enzyme binding | catalytic activity | transferase activity, transferring glycosyl groups | ion binding | protein binding | transferase activity, transferring pentosyl groups | transferase activity | metal ion binding

GO Biological Process

regulation of telomere maintenance via telomerase | positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | positive regulation of telomere capping | negative regulation of cellular process | multicellular organism growth | regulation of organelle organization | negative regulation of DNA metabolic process | positive regulation of cellular biosynthetic process | cellular process | localization | developmental growth | macromolecule localization | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | regulation of telomere capping | response to stimulus | cellular localization | negative regulation of metabolic process | protein modification process | macromolecule modification | cell-cell signaling | positive regulation of telomere maintenance via telomere lengthening | cell surface receptor signaling pathway involved in cell-cell signaling | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | Wnt signaling pathway | protein auto-ADP-ribosylation | regulation of telomere maintenance | positive regulation of chromosome organization | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | protein localization to organelle | positive regulation of telomere maintenance via telomerase | regulation of telomere maintenance via telomere lengthening | cell communication | regulation of cellular metabolic process | positive regulation of DNA biosynthetic process | positive regulation of signal transduction | negative regulation of telomere maintenance | protein polyubiquitination | protein metabolic process | regulation of growth | protein ubiquitination | protein localization to chromosome, telomeric region | protein ADP-ribosylation | cell surface receptor signaling pathway | metabolic process | cellular protein localization | organic substance metabolic process | protein modification by small protein conjugation or removal | regulation of Wnt signaling pathway | regulation of chromosome organization | positive regulation of canonical Wnt signaling pathway | regulation of cell communication | negative regulation of chromosome organization | signaling | negative regulation of telomere maintenance via telomere lengthening | regulation of developmental growth | protein localization | cellular protein metabolic process | cellular macromolecule localization | regulation of developmental process | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | developmental process | regulation of DNA biosynthetic process | cellular protein modification process | positive regulation of metabolic process | positive regulation of Wnt signaling pathway | cellular metabolic process | regulation of cellular component organization | positive regulation of signaling | protein localization to chromosome | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

chromosome | pericentriolar material | intracellular membrane-bounded organelle | organelle membrane | microtubule organizing center | cell | nuclear lumen | cytoplasm | intracellular organelle | centrosome | Golgi apparatus | endomembrane system | nuclear envelope | nuclear chromosome | perinuclear region of cytoplasm | microtubule cytoskeleton | chromosome, telomeric region | Golgi membrane | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | cytoskeleton | nuclear chromosome, telomeric region | intracellular | membrane