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QuickView for TRH (gene)


Gene Symbol:
TRH Homo sapiens Homo sapiens
Full name:
thyrotropin releasing hormone
Synonyms:
Pro-TRH, TRF, thyrotropin releasing hormone, TSH-releasing factor, pro-thyrotropin-releasing hormone, prothyroliberin, protirelin, thyrotropin-releasing factor
Genomic Location:
Chr 3: 131176253-131179470
Description:
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3q22.1


Transcripts Names
NM_007117
Protein Names
B2R8R1
P20396
Q2TB83



GO Molecular Function

signaling receptor binding | thyrotropin-releasing hormone activity | hormone activity | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity

GO Biological Process

regulation of localization | response to hormone | negative regulation of cellular process | response to drug | regulation of peptide hormone secretion | positive regulation of protein secretion | response to antibiotic | hormone-mediated signaling pathway | cellular process | regulation of gamma-aminobutyric acid secretion | negative regulation of glutamate secretion | walking behavior | negative regulation of amino acid transport | negative regulation of secretion | response to hypoxia | response to corticosterone | regulation of behavior | cellular biogenic amine metabolic process | regulation of cellular process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of peptide secretion | response to stimulus | regulation of feeding behavior | regulation of insulin secretion | histamine metabolic process | response to cold | thyrotropin-releasing hormone activity | response to stress | response to glucose | response to alcohol | response to temperature stimulus | cellular nitrogen compound metabolic process | positive regulation of hormone secretion | negative regulation of transport | hormone activity | regulation of protein transport | G-protein coupled receptor signaling pathway | amine metabolic process | regulation of peptide transport | cell-cell signaling | molecular function regulator | response to ethanol | positive regulation of peptide secretion | regulation of neurotransmitter levels | cellular response to hormone stimulus | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of secretion by cell | regulation of hormone levels | regulation of hormone secretion | positive regulation of secretion | response to ketone | response to lipid | adult walking behavior | adult locomotory behavior | response to corticosteroid | neurotransmitter metabolic process | locomotory behavior | eating behavior | negative regulation of ion transport | response to toxic substance | regulation of glutamate secretion | cell communication | response to monosaccharide | positive regulation of establishment of protein localization | positive regulation of transport | positive regulation of peptide hormone secretion | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | response to organic substance | negative regulation of behavior | positive regulation of insulin secretion | metabolic process | negative regulation of feeding behavior | response to mineralocorticoid | regulation of secretion | behavior | receptor ligand activity | organic substance metabolic process | positive regulation of amino acid transport | positive regulation of ion transport | regulation of protein secretion | positive regulation of organic acid transport | positive regulation of gamma-aminobutyric acid secretion | positive regulation of protein transport | adult behavior | regulation of cell communication | signaling | feeding behavior | response to organic cyclic compound | regulation of ion transport | positive regulation of anion transport | regulation of transport | heterocycle metabolic process | regulation of anion transport | cellular metabolic process | cellular response to organic substance | regulation of protein localization | response to carbohydrate | response to steroid hormone | positive regulation of signaling | signal transduction | regulation of signaling | response to glucocorticoid | multicellular organismal process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | secretory vesicle | endomembrane system | plasma membrane | vesicle | extracellular region | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular vesicle | intracellular | membrane