QuickView for TRHDE (gene)

Gene Symbol:

TRHDE Homo sapiens

Full name:

thyrotropin releasing hormone degrading enzyme

Synonyms:

PAP-II, PGPEP2, TRH-DE, thyrotropin-releasing hormone-degrading ectoenzyme, TRH-degrading ectoenzyme, TRH-specific aminopeptidase, pyroglutamyl aminopeptidase II, pyroglutamyl-peptidase II, thyroliberinase

Genomic Location:

Chr 12: 70952730-71345689

Description:

This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.

This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTTGAG_MIR373 ,  CAGTGTT_MIR141_MIR200A ,  CAGCACT_MIR5123P ,  GGGCATT_MIR365 ,  GACAATC_MIR219 ,  GGGTGGRR_PAX4_03 ,  AAGCACA_MIR218

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-219 ,  Predicted Gene Targets for miR-365

Cytogenetic Map:

12q21.1

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