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QuickView for TRIAD2 (gene)


Gene Symbol:
RNF14 Homo sapiens Homo sapiens
Full name:
ring finger protein 14
Synonyms:
ARA54, HFB30, HRIHFB2038, TRIAD2, E3 ubiquitin-protein ligase RNF14, androgen receptor associated protein 54
Genomic Location:
Chr 5: 141326621-141348938
Description:
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated ...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5
5q31.3





GO Molecular Function

cation binding | hormone receptor binding | enzyme binding | signaling receptor binding | catalytic activity | ubiquitin-like protein transferase activity | androgen receptor binding | ubiquitin conjugating enzyme binding | ubiquitin protein ligase activity | nuclear hormone receptor binding | ion binding | transcription coactivator activity | protein binding | transcription factor binding | ubiquitin-protein transferase activity | ubiquitin-like protein conjugating enzyme binding | transferase activity | ubiquitin-like protein ligase activity | steroid hormone receptor binding | transcription coregulator activity | metal ion binding

GO Biological Process

RNA metabolic process | positive regulation of macromolecule biosynthetic process | proteolysis | response to hormone | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | positive regulation of protein catabolic process | androgen receptor signaling pathway | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | positive regulation of cellular protein catabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | regulation of intracellular steroid hormone receptor signaling pathway | cellular nitrogen compound biosynthetic process | positive regulation of proteolysis involved in cellular protein catabolic process | cellular protein catabolic process | positive regulation of proteolysis | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | positive regulation of RNA biosynthetic process | protein modification process | steroid hormone mediated signaling pathway | cellular biosynthetic process | macromolecule modification | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | nitrogen compound metabolic process | regulation of signal transduction | regulation of gene expression | response to lipid | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | regulation of transcription by RNA polymerase II | ubiquitin protein ligase activity | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | positive regulation of proteasomal protein catabolic process | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of androgen receptor signaling pathway | transcription coactivator activity | regulation of RNA metabolic process | regulation of proteasomal ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | response to organic substance | protein ubiquitination | cellular macromolecule catabolic process | metabolic process | positive regulation of ubiquitin-dependent protein catabolic process | ubiquitin-protein transferase activity | regulation of protein catabolic process | regulation of RNA biosynthetic process | regulation of proteasomal protein catabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | protein modification by small protein conjugation or removal | cellular response to steroid hormone stimulus | transcription, DNA-templated | intracellular receptor signaling pathway | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular protein metabolic process | cellular macromolecule biosynthetic process | intracellular steroid hormone receptor signaling pathway | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | response to steroid hormone | modification-dependent protein catabolic process | regulation of ubiquitin-dependent protein catabolic process | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | cell | cytoplasm | intracellular organelle | ubiquitin ligase complex | protein-containing complex | transferase complex | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular