Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for TRIDENT (gene)


Gene Symbol:
FOXM1 Homo sapiens Homo sapiens
Full name:
forkhead box M1
Synonyms:
FKHL16, FOXM1B, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TRIDENT, forkhead box protein M1, Forkhead, drosophila, homolog-like 16, HNF-3/fork-head homolog 11, M-phase phosphoprotein 2, MPM-2 reactive phosphoprotein 2, forkhead-related protein FKHL16, hepatocyte nuclear factor 3 forkhead homolog 11, transcription factor Trident, winged-helix factor from INS-1 cells
Genomic Location:
Chr 12: 2837110-2856564
Description:
The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 12
12p13.33





GO Molecular Function

sequence-specific DNA binding | kinase binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | protein kinase binding | enzyme binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | double-stranded DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | negative regulation of phosphorylation | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | negative regulation of MAPK cascade | intracellular signal transduction | regulation of cell aging | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | negative regulation of protein phosphorylation | regulation of DNA repair | negative regulation of stress-activated protein kinase signaling cascade | positive regulation of cellular biosynthetic process | cellular process | negative regulation of signaling | negative regulation of nucleic acid-templated transcription | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | positive regulation of response to DNA damage stimulus | response to stimulus | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | regulation of double-strand break repair | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | DNA repair | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | nitrogen compound metabolic process | regulation of signal transduction | DNA damage response, signal transduction by p53 class mediator | negative regulation of phosphate metabolic process | regulation of MAPK cascade | cellular response to DNA damage stimulus | regulation of phosphorylation | DNA damage response, signal transduction resulting in transcription | signal transduction in response to DNA damage | regulation of small GTPase mediated signal transduction | regulation of gene expression | cellular response to stress | cell cycle | regulation of cell cycle arrest | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | G2/M transition of mitotic cell cycle | negative regulation of stress-activated MAPK cascade | mitotic cell cycle phase transition | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | cell cycle G2/M phase transition | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | DNA-binding transcription factor activity | DNA metabolic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | positive regulation of double-strand break repair | mitotic cell cycle | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | regulation of phosphate metabolic process | transcription, DNA-templated | negative regulation of cell aging | negative regulation of protein metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | regulation of Ras protein signal transduction | cellular macromolecule biosynthetic process | regulation of developmental process | positive regulation of DNA metabolic process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | positive regulation of nucleic acid-templated transcription | cell cycle phase transition | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | signal transduction by p53 class mediator | signal transduction | regulation of signaling | positive regulation of gene expression | positive regulation of DNA repair | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular