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QuickView for TRIM32;jsessionid=E67F4C55E6E512A8622682D946C6AAEB (gene)


Gene Symbol:
TRIM32 Homo sapiens Homo sapiens
Full name:
tripartite motif containing 32
Synonyms:
BBS11, HT2A, LGMD2H, TATIP, E3 ubiquitin-protein ligase TRIM32, 72 kDa Tat-interacting protein, RING-type E3 ubiquitin transferase TRIM32, TAT-interactive protein, 72-KD, tripartite motif-containing protein 32, zinc-finger protein HT2A
Genomic Location:
Chr 9: 118489402-118503400
Description:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 9
9q33.1





GO Molecular Function

protein self-association | translation initiation factor binding | cation binding | nucleic acid binding | myosin binding | ubiquitin binding | catalytic activity | ubiquitin-like protein transferase activity | cytoskeletal protein binding | identical protein binding | ubiquitin protein ligase activity | ubiquitin-like protein binding | ion binding | organic cyclic compound binding | transcription coactivator activity | protein binding | zinc ion binding | transcription factor binding | ubiquitin-protein transferase activity | transferase activity | transition metal ion binding | ubiquitin-like protein ligase activity | transcription coregulator activity | metal ion binding | heterocyclic compound binding | Tat protein binding | RNA binding

GO Biological Process

positive regulation of striated muscle cell differentiation | response to radiation | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | actin filament-based process | response to cytokine | regulation of neurogenesis | positive regulation of interleukin-17-mediated signaling pathway | proteolysis | regulation of cell development | regulation of localization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | negative regulation of viral release from host cell | actin cytoskeleton organization | actin ubiquitination | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | actin modification | defense response | nervous system development | positive regulation of protein catabolic process | neurogenesis | positive regulation of cellular component movement | generation of neurons | tissue homeostasis | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | regulation of cell motility | cellular homeostasis | proteolysis involved in cellular protein catabolic process | negative regulation of signaling | neuron development | negative regulation of viral life cycle | regulation of response to cytokine stimulus | negative regulation of apoptotic process | positive regulation of tumor necrosis factor-mediated signaling pathway | regulation of proteolysis | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | positive regulation of muscle cell differentiation | anatomical structure homeostasis | negative regulation of apoptotic signaling pathway | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | regulation of metabolic process | catabolic process | positive regulation of cellular protein metabolic process | regulation of viral release from host cell | cellular component organization | response to UV | regulation of type I interferon production | response to stimulus | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | multicellular organismal homeostasis | cellular protein catabolic process | positive regulation of proteolysis | positive regulation of RNA biosynthetic process | protein modification process | macromolecule modification | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | positive regulation of response to cytokine stimulus | response to light stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of intrinsic apoptotic signaling pathway | positive regulation of cell cycle | regulation of neuron differentiation | regulation of gene expression | axon development | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | regulation of cell migration | positive regulation of intracellular signal transduction | regulation of cellular component movement | fat cell differentiation | ubiquitin protein ligase activity | positive regulation of cell differentiation | negative regulation of viral process | positive regulation of cell migration | regulation of cellular protein metabolic process | muscle cell cellular homeostasis | positive regulation of chemokine production | regulation of apoptotic signaling pathway | regulation of cellular metabolic process | regulation of tumor necrosis factor-mediated signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | regulation of cytokine-mediated signaling pathway | regulation of locomotion | transcription coactivator activity | regulation of RNA metabolic process | regulation of viral process | positive regulation of molecular function | protein polyubiquitination | neuron differentiation | protein metabolic process | regulation of fibroblast proliferation | regulation of growth | response to organic substance | protein ubiquitination | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | cellular macromolecule catabolic process | anatomical structure development | positive regulation of neurogenesis | cell projection organization | metabolic process | positive regulation of cell development | ubiquitin-protein transferase activity | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | regulation of response to DNA damage stimulus | immune response | neuron projection development | organic substance metabolic process | negative regulation of intrinsic apoptotic signaling pathway | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | positive regulation of NF-kappaB transcription factor activity | protein modification by small protein conjugation or removal | regulation of striated muscle cell differentiation | cytoskeleton organization | positive regulation of cytokine production | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | positive regulation of cytokine-mediated signaling pathway | regulation of cell communication | negative regulation of signal transduction | positive regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of growth | regulation of transcription, DNA-templated | cell development | negative regulation of fibroblast proliferation | cellular protein metabolic process | regulation of cytokine production | regulation of nervous system development | regulation of developmental process | developmental process | organelle organization | regulation of muscle cell differentiation | regulation of cell growth | cellular protein modification process | regulation of chemokine production | negative regulation of cell proliferation | innate immune response | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | protein K48-linked ubiquitination | regulation of viral transcription | positive regulation of metabolic process | positive regulation of neuron differentiation | immune system process | cellular metabolic process | response to tumor necrosis factor | positive regulation of chemokine (C-C motif) ligand 20 production | regulation of cell death | positive regulation of cell motility | modification-dependent protein catabolic process | regulation of viral life cycle | negative regulation of cell death | negative regulation of locomotion | negative regulation of viral transcription | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | positive regulation of signaling | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

supramolecular fiber | intracellular membrane-bounded organelle | sarcomere | cell | myofibril | cytoplasm | intracellular organelle | actin cytoskeleton | contractile fiber | protein-containing complex | striated muscle myosin thick filament | muscle myosin complex | myosin complex | myosin filament | membrane-bounded organelle | myosin II complex | nucleus | organelle | cytosol | cytoskeleton | intracellular | supramolecular complex