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QuickView for TRPA1 (gene)


Gene Symbol:
TRPA1 Homo sapiens Homo sapiens
Full name:
transient receptor potential cation channel subfamily A member 1
Synonyms:
ANKTM1, FEPS, FEPS1, transient receptor potential cation channel subfamily A member 1, ankyrin-like with transmembrane domains 1, transformation-sensitive protein p120
Genomic Location:
Chr 8: 73096040-73150373
Description:
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Danio rerio Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 8
8q21.11


Protein Names
A6NIN6
O75762



GO Molecular Function

ligand-gated calcium channel activity | passive transmembrane transporter activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | temperature-gated cation channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | identical protein binding | ion transmembrane transporter activity | temperature-gated ion channel activity | calcium-release channel activity | protein binding | metal ion transmembrane transporter activity | cation channel activity | inorganic cation transmembrane transporter activity | intracellular ligand-gated ion channel activity | channel activity | calcium channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

protein homooligomerization | detection of stimulus | intracellular signal transduction | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | regulation of localization | ligand-gated calcium channel activity | establishment of localization | negative regulation of cellular process | detection of mechanical stimulus involved in sensory perception | response to drug | cellular chemical homeostasis | response to antibiotic | sensory perception of mechanical stimulus | cellular process | localization | cellular homeostasis | passive transmembrane transporter activity | metal ion transport | response to inorganic substance | establishment of localization in cell | response to hydrogen peroxide | regulation of cellular process | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | ligand-gated ion channel activity | cellular component organization | calcium ion homeostasis | calcium ion transport into cytosol | response to stimulus | ion gated channel activity | response to pain | response to cold | response to stress | detection of chemical stimulus involved in sensory perception | sensory perception of temperature stimulus | cellular localization | divalent metal ion transport | response to temperature stimulus | cellular component assembly | metal ion homeostasis | temperature-gated cation channel activity | detection of abiotic stimulus | detection of chemical stimulus | calcium ion transmembrane transport | protein complex oligomerization | ion transmembrane transport | detection of mechanical stimulus involved in sensory perception of pain | nervous system process | cation transmembrane transporter activity | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | protein homotetramerization | calcium ion transmembrane transporter activity | response to oxidative stress | ion transmembrane transporter activity | second-messenger-mediated signaling | negative regulation of sequestering of calcium ion | sensory perception of pain | protein tetramerization | response to toxic substance | cation homeostasis | temperature-gated ion channel activity | cellular cation homeostasis | cell communication | cellular calcium ion homeostasis | homeostatic process | calcium-release channel activity | release of sequestered calcium ion into cytosol | calcium-mediated signaling | cation transmembrane transport | protein-containing complex assembly | multicellular organismal response to stress | response to organic substance | response to mechanical stimulus | detection of stimulus involved in sensory perception | metal ion transmembrane transporter activity | cell surface receptor signaling pathway | chemical homeostasis | calcium ion transport | regulation of sequestering of calcium ion | response to reactive oxygen species | ion homeostasis | inorganic cation transmembrane transport | detection of mechanical stimulus | cation channel activity | sensory perception | thermoception | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | response to organic cyclic compound | intracellular ligand-gated ion channel activity | sensory perception of chemical stimulus | cation transport | channel activity | calcium channel activity | detection of chemical stimulus involved in sensory perception of pain | cellular metal ion homeostasis | ion channel activity | ion transport | divalent inorganic cation homeostasis | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | stereocilium bundle | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane