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QuickView for TTR (gene)

Gene Symbol:
TTR Homo sapiens Homo sapiens
Full name:
ATTR, CTS, CTS1, HEL111, HsT2651, PALB, TBPA, transthyretin, epididymis luminal protein 111, prealbumin, amyloidosis type I, thyroxine-binding prealbumin
Genomic Location:
Chr 18: 27425838-27432781
This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating ...
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 18

Transcripts Names

GO Molecular Function

signaling receptor binding | hormone activity | molecular function regulator | thyroid hormone binding | identical protein binding | protein heterodimerization activity | hormone binding | protein binding | receptor regulator activity | protein dimerization activity | receptor ligand activity

GO Biological Process

exocytosis | extracellular structure organization | neutrophil activation | establishment of localization | cellular process | secretion | leukocyte degranulation | localization | regulation of cellular process | leukocyte activation | cellular component organization | cellular lipid metabolic process | response to stimulus | neutrophil degranulation | leukocyte activation involved in immune response | alcohol metabolic process | secretion by cell | retinol metabolic process | extracellular matrix organization | hormone activity | molecular function regulator | organic hydroxy compound metabolic process | retinoid metabolic process | nitrogen compound metabolic process | regulation of signal transduction | leukocyte mediated immunity | lipid metabolic process | regulation of hormone levels | small molecule metabolic process | vesicle-mediated transport | regulated exocytosis | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | thyroid hormone transport | regulation of signaling receptor activity | receptor regulator activity | protein metabolic process | metabolic process | receptor ligand activity | immune response | hormone transport | organic substance metabolic process | diterpenoid metabolic process | cell activation | regulation of cell communication | cellular protein metabolic process | hormone metabolic process | isoprenoid metabolic process | neutrophil mediated immunity | immune system process | cellular metabolic process | regulation of signaling | macromolecule metabolic process

GO Cellular Component

secretory granule | azurophil granule lumen | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | vacuolar lumen | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | protein-containing complex | secretory vesicle | endomembrane system | vacuole | vesicle | extracellular exosome | lytic vacuole | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | lysosome | extracellular space | membrane-enclosed lumen | azurophil granule | secretory granule lumen | intracellular vesicle | intracellular | vesicle lumen