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QuickView for TUB;jsessionid=A3C18788E07A17D8B2EEEE60AB1721C4 (gene)


Gene Symbol:
TUB Homo sapiens Homo sapiens
Full name:
tubby bipartite transcription factor
Synonyms:
RDOB, rd5, tubby protein homolog, tubby homolog, tubby homologue
Genomic Location:
Chr 11: 8016756-8084228
Description:
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosph...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 11
11p15.4





GO Molecular Function

protein-containing complex binding | lipid binding | phospholipid binding | anion binding | ion binding | phosphatidylinositol binding

GO Biological Process

positive regulation of cellular component organization | protein localization to cell periphery | regulation of localization | eye development | establishment of localization | response to hormone | sensory perception of mechanical stimulus | tissue homeostasis | cellular process | localization | macromolecule localization | anatomical structure homeostasis | cell recognition | regulation of cellular process | protein localization to ciliary membrane | response to stimulus | multicellular organismal homeostasis | cellular localization | regulation of phagocytosis | system development | multicellular organism development | protein localization to non-motile cilium | protein localization to membrane | nervous system process | vesicle-mediated transport | protein localization to organelle | sensory organ development | receptor localization to non-motile cilium | sensory perception of sound | homeostatic process | positive regulation of transport | response to organic substance | retina development in camera-type eye | import into cell | phagocytosis, recognition | anatomical structure development | protein localization to photoreceptor outer segment | cellular protein localization | regulation of vesicle-mediated transport | endocytosis | animal organ development | retina homeostasis | positive regulation of phagocytosis | photoreceptor cell maintenance | camera-type eye development | sensory perception | protein localization to cilium | regulation of endocytosis | protein localization | cellular macromolecule localization | developmental process | regulation of transport | phagocytosis | positive regulation of endocytosis | regulation of cellular component organization | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | cell projection | plasma membrane | cilium | extracellular region | membrane-bounded organelle | nucleus | organelle | cell periphery | cytosol | intracellular | membrane