QuickView for TUBB (gene)

Gene Symbol:

TUBB Homo sapiens

Full name:

tubulin beta class I

Synonyms:

CDCBM6, CSCSC1, M40, OK/SW-cl.56, TUBB1, TUBB5, tubulin beta chain, beta Ib tubulin, tubulin beta-1 chain, tubulin beta-5 chain, tubulin, beta polypeptide

Genomic Location:

Chr 6: 30796136-30801178

Description:

This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes ...

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This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NRF2_Q4 ,  TAATTA_CHX10_01 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  CTTTGT_LEF1_Q2 ,  TCF11MAFG_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-200b

Cytogenetic Map:

6p21.33

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