QuickView for TULA (gene)

Gene Symbol:

UBASH3A Homo sapiens

Full name:

ubiquitin associated and SH3 domain containing A

Synonyms:

CLIP4, STS-2, TULA, TULA-1, ubiquitin-associated and SH3 domain-containing protein A, T-cell ubiquitin ligand 1, T-cell ubiquitin ligand protein, cbl-interacting protein 4, suppressor of T-cell receptor signaling 2

Genomic Location:

Chr 21: 42697088-42740843

Description:

This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of...

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This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGTTTGY_HNF3_Q6

Cytogenetic Map:

21q22.3

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