QuickView for TWA2 (gene)

Gene Symbol:

MKLN1 Homo sapiens

Full name:

muskelin 1

Synonyms:

TWA2, muskelin, muskelin 1, intracellular mediator containing kelch motifs

Genomic Location:

Chr 7: 130663175-130831931

Description:

Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).

Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AML_Q6 ,  ACTTTAT_MIR1425P ,  CTCAAGA_MIR526B ,  TGCCTTA_MIR124A ,  RACCACAR_AML_Q6 ,  GGCCAGT_MIR193A_MIR193B ,  TCCAGAG_MIR518C

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-193 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-374

Cytogenetic Map:

7q32.3

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